Amal Hofni

Qina, KN, Egypt

Last Updated: 09/26/2026

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Found 12 publications

Thiadiazolo-Triazolo-Pyrimidine Hybrids as Dual Aurora A/ERK Inhibitors: Design, Synthesis, and Apoptotic Activity.

Thiadiazolo-Triazolo-Pyrimidine Hybrids as Dual Aurora A/ERK Inhibitors: Design, Synthesis, and Apoptotic Activity.

Journal: Drug development research

Published: March 26, 2026

Celastrol Mitigates Colistin-Induced Renal Toxicity in Rats via Modulating Nrf-2/HO-1 and NF-κB Signaling Pathways.

Celastrol Mitigates Colistin-Induced Renal Toxicity in Rats via Modulating Nrf-2/HO-1 and NF-κB Signaling Pathways.

Journal: Journal of biochemical and molecular toxicology

Published: July 21, 2025

Novel inhibitors of oncogenic Wnt/TCF-4/β-catenin signaling pathway: Design, synthesis, molecular docking studies and apoptosis inducing activity of pyrimidothiazino-, dihydropyrimidotriazepino- and 1,3,4-thiadiazolopyrimido-indole hybrids.

Novel inhibitors of oncogenic Wnt/TCF-4/β-catenin signaling pathway: Design, synthesis, molecular docking studies and apoptosis inducing activity of pyrimidothiazino-, dihydropyrimidotriazepino- and 1,3,4-thiadiazolopyrimido-indole hybrids.

Journal: Bioorganic chemistry

Published: December 28, 2024

Berberine Alleviates Uterine Inflammation in Rats via Modulating the TLR-2/p-PI3K/p-AKT Axis.

Berberine Alleviates Uterine Inflammation in Rats via Modulating the TLR-2/p-PI3K/p-AKT Axis.

Journal: International immunopharmacology

Published: June 04, 2024

Celastrol protects against cisplatin-induced ovarian toxicity via modulation of PPAR-γ and AMPK.

Celastrol protects against cisplatin-induced ovarian toxicity via modulation of PPAR-γ and AMPK.

Journal: Naunyn-Schmiedeberg's archives of pharmacology

Published: March 06, 2024

Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho[2',3':4,5]thiazolo[3,2-a]pyrimidine hybrids as potential anticancer agents with apoptosis inducing activity.

Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho[2',3':4,5]thiazolo[3,2-a]pyrimidine hybrids as potential anticancer agents with apoptosis inducing activity.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: May 11, 2023

Ginger Extract-Loaded Transethosomes for Effective Transdermal Permeation and Anti-Inflammation in Rat Model.

Ginger Extract-Loaded Transethosomes for Effective Transdermal Permeation and Anti-Inflammation in Rat Model.

Journal: International journal of nanomedicine

Published: December 07, 2022

Fasudil Ameliorates Methotrexate-Induced Hepatotoxicity by Modulation of Redox-Sensitive Signals.

Fasudil Ameliorates Methotrexate-Induced Hepatotoxicity by Modulation of Redox-Sensitive Signals.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: October 01, 2022

Renoprotective Effect of Thymoquinone against Streptozotocin-Induced Diabetic Nephropathy: Role of NOX2 and Nrf2 Signals.

Renoprotective Effect of Thymoquinone against Streptozotocin-Induced Diabetic Nephropathy: Role of NOX2 and Nrf2 Signals.

Journal: Current molecular pharmacology

Published: August 07, 2022

Selective Targeting of the Novel CK-10 Nanoparticles to the MDA-MB-231 Breast Cancer Cells.

Selective Targeting of the Novel CK-10 Nanoparticles to the MDA-MB-231 Breast Cancer Cells.

Journal: Journal of pharmaceutical sciences

Published: June 13, 2021

Fasudil ameliorates endothelial dysfunction in streptozotocin-induced diabetic rats: a possible role of Rho kinase.

Fasudil ameliorates endothelial dysfunction in streptozotocin-induced diabetic rats: a possible role of Rho kinase.

Journal: Naunyn-Schmiedeberg's archives of pharmacology

Published: August 25, 2016

Combination therapy with spironolactone and candesartan protects against streptozotocin-induced diabetic nephropathy in rats.

Combination therapy with spironolactone and candesartan protects against streptozotocin-induced diabetic nephropathy in rats.

Journal: European journal of pharmacology

Published: July 05, 2014

Showing 1-12 of 12

Last Updated: 09/26/2026