Last Updated: 09/26/2026
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Found 23 publications
Inhibition of adenylyl cyclase 1 or exchange protein activated by cAMP restores ATP-sensitive potassium channel activity after chronic opioid exposure.
Journal: British journal of pharmacology
Published: November 04, 2025
Inhibition of adenylyl cyclase 1 (AC1) and exchange protein directly activated by cAMP (EPAC) restores ATP-sensitive potassium (KATP) channel activity after chronic opioid exposure.
Journal: bioRxiv : the preprint server for biology
Published: February 20, 2025
Pharmacologically enabling the degradation of Na V 1.8 channels to reduce neuropathic pain.
Journal: Pain
Published: May 20, 2024
Loss of ATP-Sensitive Potassium Channel Expression and Function in the Nervous System Decreases Opioid Sensitivity in a High-Fat Diet-Fed Mouse Model of Diet-Induced Obesity.
Journal: Diabetes
Published: December 26, 2023
Loss of ATP-sensitive channel expression and function decreases opioid sensitivity in a mouse model of type 2 diabetes.
Journal: bioRxiv : the preprint server for biology
Published: September 21, 2023
KATP Channel Prodrugs Reduce Inflammatory and Neuropathic Hypersensitivity, Morphine-Induced Hypersensitivity, and Precipitated Withdrawal in Mice.
Journal: The Journal of pharmacology and experimental therapeutics
Published: November 23, 2022
Reduced activity of adenylyl cyclase 1 attenuates morphine induced hyperalgesia and inflammatory pain in mice.
Journal: Frontiers in pharmacology
Published: May 06, 2022
The Role of Patient-reported Outcomes and Medication Adherence Assessment in Patient-focused Drug Development for Solid Organ Transplantation.
Journal: Transplantation
Published: April 26, 2021
Inhibition of the phosphoinositide 3-kinase-AKT-cyclic GMP-c-Jun N-terminal kinase signaling pathway attenuates the development of morphine tolerance in a mouse model of neuropathic pain.
Journal: Molecular pain
Published: March 22, 2021
Loss of SUR1 subtype KATP channels alters antinociception and locomotor activity after opioid administration.
Journal: Behavioural brain research
Published: December 14, 2020
Last Updated: 09/26/2026