Amandeep Thakur

250 Wuxing Street
Taipei, TNQ 11031, Taiwan

Last Updated: 09/26/2026

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Found 24 publications

Dual SYK-HDAC Inhibitor Elicits Striking Efficacy against Acute Myeloid Leukemia: Rational Design, Synthesis, and Biological Evaluation.

Dual SYK-HDAC Inhibitor Elicits Striking Efficacy against Acute Myeloid Leukemia: Rational Design, Synthesis, and Biological Evaluation.

Journal: Journal of medicinal chemistry

Published: June 09, 2026

KDM1A/HDAC2-driven epigenetic dysregulation maintains a drug-resistant, relapse-initiating glioblastoma cell niche at the peri-tumoral margin.

KDM1A/HDAC2-driven epigenetic dysregulation maintains a drug-resistant, relapse-initiating glioblastoma cell niche at the peri-tumoral margin.

Journal: Biochemical pharmacology

Published: February 23, 2026

Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics.

Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: February 16, 2026

Multi-Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns.

Multi-Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns.

Journal: Medicinal research reviews

Published: September 06, 2025

Contribution of Prostaglandin E2-Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood-Brain Barrier Crossing Celecoxib Derivative.

Contribution of Prostaglandin E2-Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood-Brain Barrier Crossing Celecoxib Derivative.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: April 08, 2025

Advancing glioblastoma therapy: Learning from the past and innovations for the future.

Advancing glioblastoma therapy: Learning from the past and innovations for the future.

Journal: Cancer letters

Published: November 14, 2024

Scaffold hopping approaches for dual-target antitumor drug discovery: opportunities and challenges.

Scaffold hopping approaches for dual-target antitumor drug discovery: opportunities and challenges.

Journal: Expert opinion on drug discovery

Published: October 18, 2024

Spleen tyrosine kinase (SYK): an emerging target for the assemblage of small molecule antitumor agents.

Spleen tyrosine kinase (SYK): an emerging target for the assemblage of small molecule antitumor agents.

Journal: Expert opinion on investigational drugs

Published: August 03, 2024

Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation.

Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation.

Journal: European journal of medicinal chemistry

Published: March 26, 2024

Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.

Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.

Journal: European journal of medicinal chemistry

Published: March 07, 2024

Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer.

Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: November 03, 2023

Small molecule tractable PARP inhibitors: Scaffold construction approaches, mechanistic insights and structure activity relationship.

Small molecule tractable PARP inhibitors: Scaffold construction approaches, mechanistic insights and structure activity relationship.

Journal: Bioorganic chemistry

Published: August 09, 2023

Showing 1-12 of 24

Last Updated: 09/26/2026