Ambra Gianotti

Genoa, Italy

Last Updated: 09/26/2026

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Found 18 publications

KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model.

KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model.

Journal: Physiological genomics

Published: June 06, 2022

A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.

A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.

Journal: Science translational medicine

Published: March 30, 2022

The Application of Bicarbonate Recovers the Chemical-Physical Properties of Airway Surface Liquid in Cystic Fibrosis Epithelia Models.

The Application of Bicarbonate Recovers the Chemical-Physical Properties of Airway Surface Liquid in Cystic Fibrosis Epithelia Models.

Journal: Biology

Published: February 05, 2021

Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators.

Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators.

Journal: Journal of medicinal chemistry

Published: September 18, 2020

Lack of Kcnn4 improves mucociliary clearance in muco-obstructive lung disease.

Lack of Kcnn4 improves mucociliary clearance in muco-obstructive lung disease.

Journal: JCI insight

Published: May 08, 2020

Small Molecule Anion Carriers Correct Abnormal Airway Surface Liquid Properties in Cystic Fibrosis Airway Epithelia.

Small Molecule Anion Carriers Correct Abnormal Airway Surface Liquid Properties in Cystic Fibrosis Airway Epithelia.

Journal: International journal of molecular sciences

Published: December 20, 2019

Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel.

Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel.

Journal: Science advances

Published: August 01, 2019

In vitro Methods for the Development and Analysis of Human Primary Airway Epithelia.

In vitro Methods for the Development and Analysis of Human Primary Airway Epithelia.

Journal: Frontiers in pharmacology

Published: August 01, 2018

Intermolecular Interactions in the TMEM16A Dimer Controlling Channel Activity.

Intermolecular Interactions in the TMEM16A Dimer Controlling Channel Activity.

Journal: Scientific reports

Published: August 22, 2016

Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release.

Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release.

Journal: Scientific reports

Published: June 13, 2016

Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways.

Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways.

Journal: European journal of pharmacology

Published: November 06, 2015

Pharmacological rescue of mutant CFTR protein improves the viscoelastic properties of CF mucus.

Pharmacological rescue of mutant CFTR protein improves the viscoelastic properties of CF mucus.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

Published: September 25, 2015

Showing 1-12 of 18

Last Updated: 09/26/2026