Amira M. Youssef-Abo

Bani Suwayf, BNS, Egypt

Last Updated: 09/26/2026

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Found 40 publications

Farnesol mitigates methotrexate-induced intestinal toxicity by enhancing SIRT1, PPAR-γ, and Nrf2 signaling and attenuating Bax/cytochrome c/caspase-3-mediated apoptosis.

Farnesol mitigates methotrexate-induced intestinal toxicity by enhancing SIRT1, PPAR-γ, and Nrf2 signaling and attenuating Bax/cytochrome c/caspase-3-mediated apoptosis.

Journal: Immunopharmacology and immunotoxicology

Published: November 12, 2025

Buspirone combats cyclophosphamide-provoked hepatotoxicity in rats via activation of AMPK/Nrf2/HO-1 and suppression of NF-κB p65 /NLRP3 inflammasome pathways.

Buspirone combats cyclophosphamide-provoked hepatotoxicity in rats via activation of AMPK/Nrf2/HO-1 and suppression of NF-κB p65 /NLRP3 inflammasome pathways.

Journal: Naunyn-Schmiedeberg's archives of pharmacology

Published: August 13, 2025

Unraveling chemotherapy-evoked hepatic dysfunction: a deep dive into cyclophosphamide-related liver injury.

Unraveling chemotherapy-evoked hepatic dysfunction: a deep dive into cyclophosphamide-related liver injury.

Journal: Naunyn-Schmiedeberg's archives of pharmacology

Published: June 12, 2025

Comparative Efficacy of Donepezil and Lamotrigine in Modulating NFκB, PPARγ, and NLRP3 Inflammasome Pathways in Experimental Colitis.

Comparative Efficacy of Donepezil and Lamotrigine in Modulating NFκB, PPARγ, and NLRP3 Inflammasome Pathways in Experimental Colitis.

Journal: Archiv der Pharmazie

Published: May 20, 2025

Piribedil and thymol mitigate vancomycin-evoked nephrotoxicity in rats through modulation of Keap-1/Nrf2/HO-1 and NF-κB/Bax/caspase 3 signalings.

Piribedil and thymol mitigate vancomycin-evoked nephrotoxicity in rats through modulation of Keap-1/Nrf2/HO-1 and NF-κB/Bax/caspase 3 signalings.

Journal: Drug and chemical toxicology

Published: March 27, 2025

Sildenafil abrogates radiation-induced hepatotoxicity in animal model: The impact of NF-κB-p65, P53, Nrf2, and SIRT 1 pathway.

Sildenafil abrogates radiation-induced hepatotoxicity in animal model: The impact of NF-κB-p65, P53, Nrf2, and SIRT 1 pathway.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Published: October 20, 2024

The enteroprotective effect of nifuroxazide against methotrexate-induced intestinal injury involves co-activation of PPAR-γ, SIRT1, Nrf2, and suppression of NF-κB and JAK1/STAT3 signals.

The enteroprotective effect of nifuroxazide against methotrexate-induced intestinal injury involves co-activation of PPAR-γ, SIRT1, Nrf2, and suppression of NF-κB and JAK1/STAT3 signals.

Journal: International immunopharmacology

Published: September 28, 2023

Zafirlukast protects against hepatic ischemia-reperfusion injury in rats via modulating Bcl-2/Bax and NF-κB/SMAD-4 pathways.

Zafirlukast protects against hepatic ischemia-reperfusion injury in rats via modulating Bcl-2/Bax and NF-κB/SMAD-4 pathways.

Journal: International immunopharmacology

Published: February 24, 2023

Multiple targets of Nrf 2 inhibitor; trigonelline in combating urethane-induced lung cancer by caspase-executioner apoptosis, cGMP and limitation of cyclin D1 and Bcl2.

Multiple targets of Nrf 2 inhibitor; trigonelline in combating urethane-induced lung cancer by caspase-executioner apoptosis, cGMP and limitation of cyclin D1 and Bcl2.

Journal: European review for medical and pharmacological sciences

Published: January 02, 2023

Carvacrol mitigates vancomycin-induced nephrotoxicity via regulation of IkBα/p38MAPK and Keap1/Nrf2 signaling pathways: an experimental study with in silico evidence.

Carvacrol mitigates vancomycin-induced nephrotoxicity via regulation of IkBα/p38MAPK and Keap1/Nrf2 signaling pathways: an experimental study with in silico evidence.

Journal: European review for medical and pharmacological sciences

Published: December 16, 2022

Protective effects of rivaroxaban against cisplatin-induced testicular damage in rats: Impact on oxidative stress, coagulation, and p-NF-κB/VCAM-1 signaling.

Protective effects of rivaroxaban against cisplatin-induced testicular damage in rats: Impact on oxidative stress, coagulation, and p-NF-κB/VCAM-1 signaling.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Published: June 11, 2022

Retraction notice to "Empagliflozin and neohesperidin mitigate methotrexate hepatotoxicity via Nrf2/PPARγ/HO-1 signalling initiation and suppression of NF-κB/Keap1/HSP70/caspase-3 axis in rats" [Life Sci. 278 (2021) 119638].

Retraction notice to "Empagliflozin and neohesperidin mitigate methotrexate hepatotoxicity via Nrf2/PPARγ/HO-1 signalling initiation and suppression of NF-κB/Keap1/HSP70/caspase-3 axis in rats" [Life Sci. 278 (2021) 119638].

Journal: Life sciences

Published: February 18, 2022

Showing 1-12 of 40

Last Updated: 09/26/2026