Amro Elgheznawy

Frankfurt Am Main, HE, Germany

Last Updated: 09/26/2026

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Found 15 publications

Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62.

Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62.

Journal: Haematologica
Published: August 19, 2024

Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to thrombin and accelerates thrombus formation in vivo.

Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to thrombin and accelerates thrombus formation in vivo.

Journal: Frontiers in immunology
Published: March 31, 2023

Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes.

Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes.

Journal: Blood
Published: October 02, 2020

Platelet-derived calpain cleaves the endothelial protease-activated receptor 1 to induce vascular inflammation in diabetes.

Platelet-derived calpain cleaves the endothelial protease-activated receptor 1 to induce vascular inflammation in diabetes.

Journal: Basic research in cardiology
Published: July 29, 2020

Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets.

Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets.

Journal: Blood
Published: December 17, 2019

Platelet-Enriched MicroRNAs and Cardiovascular Homeostasis.

Platelet-Enriched MicroRNAs and Cardiovascular Homeostasis.

Journal: Antioxidants & redox signaling
Published: August 11, 2017

VASP regulates leukocyte infiltration, polarization, and vascular repair after ischemia.

VASP regulates leukocyte infiltration, polarization, and vascular repair after ischemia.

Journal: The Journal of cell biology
Published: February 08, 2017

Calpain 1 cleaves and inactivates prostacyclin synthase in mesenteric arteries from diabetic mice.

Calpain 1 cleaves and inactivates prostacyclin synthase in mesenteric arteries from diabetic mice.

Journal: Basic research in cardiology
Published: August 17, 2016

miR-223-IGF-IR signalling in hypoxia- and load-induced right-ventricular failure: a novel therapeutic approach.

miR-223-IGF-IR signalling in hypoxia- and load-induced right-ventricular failure: a novel therapeutic approach.

Journal: Cardiovascular research
Published: November 13, 2015

Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes.

Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes.

Journal: Circulation research
Published: December 04, 2014

Metformin reduces hyper-reactivity of platelets from patients with polycystic ovary syndrome by improving mitochondrial integrity.

Metformin reduces hyper-reactivity of platelets from patients with polycystic ovary syndrome by improving mitochondrial integrity.

Journal: Thrombosis and haemostasis
Published: September 25, 2014

MicroRNA-223 antagonizes angiogenesis by targeting β1 integrin and preventing growth factor signaling in endothelial cells.

MicroRNA-223 antagonizes angiogenesis by targeting β1 integrin and preventing growth factor signaling in endothelial cells.

Journal: Circulation research
Published: September 19, 2013
Showing 1-12 of 15

Last Updated: 09/26/2026