An De Bondt

Janssen R&D
Beerse, VLG, Belgium

Last Updated: 09/26/2026

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Found 20 publications

Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease.

Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease.

Journal: Molecular neurodegeneration

Published: November 24, 2023

Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?

Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?

Journal: European journal of pharmacology

Published: March 08, 2022

Diversity and Clonality of T Cell Receptor Repertoire and Antigen Specificities in Small Joints of Early Rheumatoid Arthritis.

Diversity and Clonality of T Cell Receptor Repertoire and Antigen Specificities in Small Joints of Early Rheumatoid Arthritis.

Journal: Arthritis & rheumatology (Hoboken, N.J.)

Published: February 13, 2022

Mutated Toll-like receptor 9 increases Alzheimer's disease risk by compromising innate immunity protection.

Mutated Toll-like receptor 9 increases Alzheimer's disease risk by compromising innate immunity protection.

Journal: Molecular psychiatry

Published: October 15, 2021

Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice.

Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice.

Journal: Acta neuropathologica communications

Published: July 19, 2021

Drug-specific T-cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat.

Drug-specific T-cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat.

Journal: Allergy

Published: July 18, 2020

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.

Journal: Stem cell reports

Published: August 15, 2019

Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons.

Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons.

Journal: European journal of pharmacology

Published: February 18, 2019

Correction: MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells.

Correction: MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells.

Journal: Bioscience reports

Published: December 04, 2018

High-Throughput Gene Expression Profiles to Define Drug Similarity and Predict Compound Activity.

High-Throughput Gene Expression Profiles to Define Drug Similarity and Predict Compound Activity.

Journal: Assay and drug development technologies

Published: April 17, 2018

Do in vitro assays in rat primary neurons predict drug-induced seizure liability in humans?

Do in vitro assays in rat primary neurons predict drug-induced seizure liability in humans?

Journal: Toxicology and applied pharmacology

Published: January 15, 2018

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.

Journal: Stem cell reports

Published: September 30, 2017

Showing 1-12 of 20

Last Updated: 09/26/2026