Ana Garcera

Institut De Recerca Biomèdica De Lleida Fundació Dr Pifarré
Lleida, CT, Spain

Last Updated: 09/26/2026

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Found 18 publications

Antisense oligonucleotides treatment uncovers differences in the modulation of dysregulated intracellular pathways in Spinal Muscular Atrophy motoneurons.

Antisense oligonucleotides treatment uncovers differences in the modulation of dysregulated intracellular pathways in Spinal Muscular Atrophy motoneurons.

Journal: Cell death & disease

Published: December 09, 2025

Inhibition of acid sphingomyelinase increases SMN levels and connects sphingolipid metabolism to Spinal Muscular Atrophy.

Inhibition of acid sphingomyelinase increases SMN levels and connects sphingolipid metabolism to Spinal Muscular Atrophy.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: May 22, 2025

TDP-43 dysfunction leads to bioenergetic failure and lipid metabolic rewiring in human cells.

TDP-43 dysfunction leads to bioenergetic failure and lipid metabolic rewiring in human cells.

Journal: Redox biology

Published: June 04, 2024

ERK MAPK signaling pathway inhibition as a potential target to prevent autophagy alterations in Spinal Muscular Atrophy motoneurons.

ERK MAPK signaling pathway inhibition as a potential target to prevent autophagy alterations in Spinal Muscular Atrophy motoneurons.

Journal: Cell death discovery

Published: February 09, 2023

Survival motor neuron protein and neurite degeneration are regulated by Gemin3 in spinal muscular atrophy motoneurons.

Survival motor neuron protein and neurite degeneration are regulated by Gemin3 in spinal muscular atrophy motoneurons.

Journal: Frontiers in cellular neuroscience

Published: September 26, 2022

Spinal Muscular Atrophy autophagy profile is tissue-dependent: differential regulation between muscle and motoneurons.

Spinal Muscular Atrophy autophagy profile is tissue-dependent: differential regulation between muscle and motoneurons.

Journal: Acta neuropathologica communications

Published: May 03, 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Journal: Autophagy

Published: February 26, 2021

Intracellular pathways involved in cell survival are deregulated in mouse and human spinal muscular atrophy motoneurons.

Intracellular pathways involved in cell survival are deregulated in mouse and human spinal muscular atrophy motoneurons.

Journal: Neurobiology of disease

Published: January 07, 2021

Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models.

Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models.

Journal: Cell death & disease

Published: October 24, 2019

Sp1-regulated expression of p11 contributes to motor neuron degeneration by membrane insertion of TASK1.

Sp1-regulated expression of p11 contributes to motor neuron degeneration by membrane insertion of TASK1.

Journal: Nature communications

Published: August 31, 2018

Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice.

Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice.

Journal: Molecular neurobiology

Published: August 01, 2018

Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy.

Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy.

Journal: Cell death & disease

Published: July 08, 2017

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Last Updated: 09/26/2026