Ana M. Martinez
Madrid, MD 28040, Spain
Last Updated: 09/26/2026
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Found 128 publications
Selective Brain-Penetrant TTBK1 Inhibitors Modulate TDP-43 Pathology and Rescue Cognitive Deficits in a Mouse Model of TDP-43 Proteinopathy.
Journal: Journal of medicinal chemistry
Published: June 14, 2026
Design, synthesis, and pharmacological evaluation of thiazolo[5,4-d]pyrimidines hybridized with lipoic acid or catechol. Novel A2A adenosine receptor antagonists in neuroinflammatory diseases.
Journal: Bioorganic chemistry
Published: May 15, 2026
Innovative therapies under clinical development for ALS treatment: small molecules.
Journal: Expert opinion on investigational drugs
Published: April 28, 2026
Nanotechnology-based encapsulation of neflamapimod: A new therapeutic strategy for lewy body dementia.
Journal: Colloids and surfaces. B, Biointerfaces
Published: March 18, 2026
Brain Permeable SGK1 Inhibitors: A Promising Therapeutic Strategy for Neurodegenerative Diseases.
Journal: Journal of medicinal chemistry
Published: March 16, 2026
Identification of Potential Multitarget Directed Ligands for Alzheimer's Disease by Coupling Virtual Screening and Experimental Validation.
Journal: Journal of chemical information and modeling
Published: February 23, 2026
Assessment of the therapeutic effect of IGS2.7, a CK1δ protein kinase inhibitor, in combination with riluzole for the treatment of ALS-associated TDP-43 proteinopathy.
Journal: Neuropharmacology
Published: October 04, 2025
Design, Synthesis and Biological Evaluation of Chromeno[3,4-b]xanthones as Multifunctional Agents for Alzheimer's Disease.
Journal: ACS chemical neuroscience
Published: August 06, 2025
Screening Natural Phenolic Compounds for Blood-Brain Barrier Permeability, Alongside GSK-3β, CK-1δ, and AChE Inhibition, for the Treatment of Alzheimer's Disease.
Journal: Drug development research
Published: May 02, 2025
Structure-Based Discovery Targeting GSK-3α Reveals Potent Nanomolar Selective 4-Phenyl-1H-benzofuro[3,2-b]pyrazolo[4,3-e]pyridine Inhibitor with Promising Glioblastoma and CNS-Active Potential in Cellular Models.
Journal: Journal of medicinal chemistry
Published: April 08, 2025
Last Updated: 09/26/2026