Ana M. Cosialls
Barcelona, CT, Spain
Last Updated: 09/26/2026
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Found 16 publications
Targeting prohibitins activates the ISR through DELE1-HRI by impairing protein import into the mitochondrial matrix.
Journal: Cell death and differentiation
Published: January 02, 2025
The prohibitin-binding compound fluorizoline induces the pro-inflammatory cytokines interleukin-8 and interleukin-6 through the activation of JNK and p38 MAP kinases.
Journal: Biochemical pharmacology
Published: July 26, 2023
The Prohibitin-Binding Compound Fluorizoline Activates the Integrated Stress Response through the eIF2α Kinase HRI.
Journal: International journal of molecular sciences
Published: March 24, 2023
Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines.
Journal: International journal of molecular sciences
Published: April 02, 2021
The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells.
Journal: Oncogenesis
Published: March 26, 2021
Fluorizoline-induced apoptosis requires prohibitins in nematodes and human cells.
Journal: Apoptosis : an international journal on programmed cell death
Published: December 11, 2020
The BCL-2 family members NOXA and BIM mediate fluorizoline-induced apoptosis in multiple myeloma cells.
Journal: Biochemical pharmacology
Published: April 14, 2020
NOXA upregulation by the prohibitin-binding compound fluorizoline is transcriptionally regulated by integrated stress response-induced ATF3 and ATF4.
Journal: The FEBS journal
Published: February 27, 2020
GRP94 promotes brain metastasis by engaging pro-survival autophagy.
Journal: Neuro-oncology
Published: October 23, 2019
Targeting prohibitins induces apoptosis in acute myeloid leukemia cells.
Journal: Oncotarget
Published: February 10, 2016
Last Updated: 09/26/2026