Anass Chiki

Lausanne, VD, Switzerland

Last Updated: 09/26/2026

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Found 19 publications

Differential role of C-terminal truncations on alpha-synuclein pathology and Lewy body formation.

Differential role of C-terminal truncations on alpha-synuclein pathology and Lewy body formation.

Journal: NPJ Parkinson's disease

Published: November 10, 2024

Deep Learning-Assisted Single-Molecule Detection of Protein Post-translational Modifications with a Biological Nanopore.

Deep Learning-Assisted Single-Molecule Detection of Protein Post-translational Modifications with a Biological Nanopore.

Journal: ACS nano

Published: December 19, 2023

Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity.

Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity.

Journal: NPJ Parkinson's disease

Published: March 29, 2022

Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.

Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.

Journal: Scientific reports

Published: June 18, 2021

The Nt17 Domain and its Helical Conformation Regulate the Aggregation, Cellular Properties and Neurotoxicity of Mutant Huntingtin Exon 1.

The Nt17 Domain and its Helical Conformation Regulate the Aggregation, Cellular Properties and Neurotoxicity of Mutant Huntingtin Exon 1.

Journal: Journal of molecular biology

Published: May 12, 2021

Investigating Crosstalk Among PTMs Provides Novel Insight Into the Structural Basis Underlying the Differential Effects of Nt17 PTMs on Mutant Httex1 Aggregation.

Investigating Crosstalk Among PTMs Provides Novel Insight Into the Structural Basis Underlying the Differential Effects of Nt17 PTMs on Mutant Httex1 Aggregation.

Journal: Frontiers in molecular biosciences

Published: March 26, 2021

Site-Specific Phosphorylation of Huntingtin Exon 1 Recombinant Proteins Enabled by the Discovery of Novel Kinases.

Site-Specific Phosphorylation of Huntingtin Exon 1 Recombinant Proteins Enabled by the Discovery of Novel Kinases.

Journal: Chembiochem : a European journal of chemical biology

Published: July 23, 2020

Unraveling the complexity of amyloid polymorphism using gold nanoparticles and cryo-EM.

Unraveling the complexity of amyloid polymorphism using gold nanoparticles and cryo-EM.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: March 13, 2020

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.

Journal: The EMBO journal

Published: February 11, 2020

Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau.

Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau.

Journal: The Journal of biological chemistry

Published: December 31, 2019

Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity.

Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity.

Journal: Nature communications

Published: September 23, 2019

A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of α-synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α-synuclein research.

A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of α-synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α-synuclein research.

Journal: Journal of neurochemistry

Published: September 16, 2019

Showing 1-12 of 19

Last Updated: 09/26/2026