Andrea Kiessling

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 17 publications

Immunogenicity risk assessment for tailored mitigation and monitoring of biotherapeutics during development: recommendations from the European Immunogenicity Platform.

Immunogenicity risk assessment for tailored mitigation and monitoring of biotherapeutics during development: recommendations from the European Immunogenicity Platform.

Journal: Frontiers in immunology

Published: February 21, 2025

Current nonclinical approaches for immune assessments of immuno-oncology biotherapeutics.

Current nonclinical approaches for immune assessments of immuno-oncology biotherapeutics.

Journal: Drug discovery today

Published: June 23, 2022

Challenges of non-clinical safety testing for biologics: A Report of the 9th BioSafe European Annual General Membership Meeting.

Challenges of non-clinical safety testing for biologics: A Report of the 9th BioSafe European Annual General Membership Meeting.

Journal: mAbs

Published: July 09, 2021

Nonclinical Development of Biologics: Integrating Safety, Pharmacokinetics, and Pharmacodynamics to Create Smarter and More Flexible Nonclinical Safety Programs Optimizing Animal Use.

Nonclinical Development of Biologics: Integrating Safety, Pharmacokinetics, and Pharmacodynamics to Create Smarter and More Flexible Nonclinical Safety Programs Optimizing Animal Use.

Journal: International journal of toxicology

Published: February 26, 2021

Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studies.

Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studies.

Journal: Regulatory toxicology and pharmacology : RTP

Published: October 01, 2020

Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration.

Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration.

Journal: mAbs

Published: August 22, 2018

Evaluation of in vitro Assays to Assess the Modulation of Dendritic Cells Functions by Therapeutic Antibodies and Aggregates.

Evaluation of in vitro Assays to Assess the Modulation of Dendritic Cells Functions by Therapeutic Antibodies and Aggregates.

Journal: Frontiers in immunology

Published: May 11, 2018

Biotherapeutics in non-clinical development: Strengthening the interface between safety, pharmacokinetics-pharmacodynamics and manufacturing.

Biotherapeutics in non-clinical development: Strengthening the interface between safety, pharmacokinetics-pharmacodynamics and manufacturing.

Journal: Regulatory toxicology and pharmacology : RTP

Published: January 09, 2018

Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions.

Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions.

Journal: Scientific reports

Published: April 10, 2017

In vitro assays supporting the safety assessment of immunomodulatory monoclonal antibodies.

In vitro assays supporting the safety assessment of immunomodulatory monoclonal antibodies.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: December 23, 2016

Translational immunotoxicology of immunomodulatory monoclonal antibodies.

Translational immunotoxicology of immunomodulatory monoclonal antibodies.

Journal: Drug discovery today. Technologies

Published: June 01, 2016

Nonclinical safety testing of biopharmaceuticals--Addressing current challenges of these novel and emerging therapies.

Nonclinical safety testing of biopharmaceuticals--Addressing current challenges of these novel and emerging therapies.

Journal: Regulatory toxicology and pharmacology : RTP

Published: July 13, 2015

Showing 1-12 of 17

Last Updated: 09/26/2026