Andrea Stutz

Bonn, NW 53127, Germany

Last Updated: 09/26/2026

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Found 10 publications

Correction to "Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor".

Correction to "Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor".

Journal: Journal of medicinal chemistry

Published: April 01, 2025

Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor.

Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor.

Journal: Journal of medicinal chemistry

Published: March 04, 2025

NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain.

NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain.

Journal: The Journal of experimental medicine

Published: June 19, 2016

Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase.

Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase.

Journal: The Journal of allergy and clinical immunology

Published: April 08, 2016

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

Journal: Nature medicine

Published: October 23, 2014

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.

Journal: Nature immunology

Published: March 31, 2014

ASC speck formation as a readout for inflammasome activation.

ASC speck formation as a readout for inflammasome activation.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: July 16, 2013

Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.

Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.

Journal: Cell reports

Published: July 07, 2013

Activation and regulation of the inflammasomes.

Activation and regulation of the inflammasomes.

Journal: Nature reviews. Immunology

Published: May 25, 2013

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.

Journal: Nature

Published: February 26, 2012

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Last Updated: 09/26/2026