Andreas B. Brink
Basel, BS 4070, Switzerland
Last Updated: 09/26/2026
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Found 27 publications
Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers.
Journal: Molecular therapy. Nucleic acids
Published: January 14, 2022
Addressing Today's Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier Risdiplam.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: June 03, 2021
Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats.
Journal: Toxicologic pathology
Published: June 01, 2021
In vitro and clinical investigations to determine the drug-drug interaction potential of entrectinib, a small molecule inhibitor of neurotrophic tyrosine receptor kinase (NTRK).
Journal: Investigational new drugs
Published: April 15, 2021
Multiorgan Crystal Deposition of an Amphoteric Drug in Rats Due to Lysosomal Accumulation and Conversion to a Poorly Soluble Hydrochloride Salt.
Journal: Toxicological sciences : an official journal of the Society of Toxicology
Published: January 17, 2021
Characterization of the pharmacokinetics of entrectinib and its active M5 metabolite in healthy volunteers and patients with solid tumors.
Journal: Investigational new drugs
Published: October 30, 2020
Detecting cocoa plantations in Côte d'Ivoire and Ghana and their implications on protected areas.
Journal: Ecological indicators
Published: September 02, 2020
Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.
Journal: Journal of medicinal chemistry
Published: August 14, 2020
Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease.
Journal: Journal of the American Society of Nephrology : JASN
Published: April 27, 2020
Genotoxicity Assessment of Drug Metabolites in the Context of MIST and Beyond.
Journal: Chemical research in toxicology
Published: December 21, 2019
Structure-Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.
Journal: Journal of medicinal chemistry
Published: November 22, 2019
Studying the Biotransformation of Phosphorothioate-Containing Oligonucleotide Drugs by LC-MS.
Journal: Methods in molecular biology (Clifton, N.J.)
Published: August 15, 2019
Last Updated: 09/26/2026