Andreas Ebneth

Beerse, VLG 2340, Belgium

Last Updated: 09/26/2026

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Found 28 publications

Discovery of 5‑Azaindole Inhibitors of O‑GlcNAcase for the Treatment of Alzheimer's Disease and Related Tauopathies.

Discovery of 5‑Azaindole Inhibitors of O‑GlcNAcase for the Treatment of Alzheimer's Disease and Related Tauopathies.

Journal: ACS medicinal chemistry letters
Published: January 07, 2026

Generation of three isogenic, gene-edited iPSC lines carrying the APOE-Christchurch mutation into the three common APOE variants: APOE2Ch, APOE3Ch and APOE4Ch.

Generation of three isogenic, gene-edited iPSC lines carrying the APOE-Christchurch mutation into the three common APOE variants: APOE2Ch, APOE3Ch and APOE4Ch.

Journal: Stem cell research
Published: July 12, 2023

IP-LC-MSMS Enables Identification of Three Tau O-GlcNAcylation Sites as O-GlcNAcase Inhibition Pharmacodynamic Readout in Transgenic Mice Overexpressing Human Tau.

IP-LC-MSMS Enables Identification of Three Tau O-GlcNAcylation Sites as O-GlcNAcase Inhibition Pharmacodynamic Readout in Transgenic Mice Overexpressing Human Tau.

Journal: Journal of proteome research
Published: March 08, 2023

Scalable expansion of iPSC and their derivatives across multiple lineages.

Scalable expansion of iPSC and their derivatives across multiple lineages.

Journal: Reproductive toxicology (Elmsford, N.Y.)
Published: December 28, 2021

Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.

Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.

Journal: Scientific reports
Published: June 18, 2021

SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System.

SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System.

Journal: Stem cell reviews and reports
Published: April 29, 2021

Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease.

Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease.

Journal: Stem cell research
Published: December 17, 2020

Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus.

Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus.

Journal: Stem cell research
Published: December 03, 2020

Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies.

Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies.

Journal: Stem cell research
Published: December 02, 2020

Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders.

Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders.

Journal: Journal of medicinal chemistry
Published: November 16, 2020

Corrigendum to "Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line" [Stem Cell Res. 34/1873-5061 (2019) 101349-55].

Corrigendum to "Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line" [Stem Cell Res. 34/1873-5061 (2019) 101349-55].

Journal: Stem cell research
Published: September 24, 2020

Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand.

Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand.

Journal: Journal of medicinal chemistry
Published: July 15, 2020
Showing 1-12 of 28

Last Updated: 09/26/2026