Andreas Reichel
Pharma R&D, Bayer AG
Berlin, BE, Germany
Berlin, BE, Germany
Last Updated: 09/26/2026
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Found 31 publications
PBPK Modelling of PROTACs: Learnings from ARV-110 as a Case Example.
Journal: The AAPS journal
Published: October 08, 2025
Finding a needle in the haystack: ADME and pharmacokinetics/pharmacodynamics characterization and optimization toward orally available bifunctional protein degraders.
Journal: Expert opinion on drug discovery
Published: February 16, 2025
Exploring the Potential of Adaptive, Local Machine Learning in Comparison to the Prediction Performance of Global Models: A Case Study from Bayer's Caco-2 Permeability Database.
Journal: Journal of chemical information and modeling
Published: November 20, 2024
PK/PD modeling of targeted protein degraders: Charting new waters and navigating the shallows.
Journal: Drug discovery today
Published: November 08, 2024
Transforming the Discovery of Targeted Protein Degraders: The Translational Power of Predictive PK/PD Modeling.
Journal: Clinical pharmacology and therapeutics
Published: December 13, 2023
Trends in Molecular Properties, Bioavailability, and Permeability across the Bayer Compound Collection.
Journal: Journal of medicinal chemistry
Published: February 08, 2023
A Mechanistic Pharmacodynamic Modeling Framework for the Assessment and Optimization of Proteolysis Targeting Chimeras (PROTACs).
Journal: Pharmaceutics
Published: November 23, 2022
Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain-a Game Changing Parameter for CNS Drug Discovery and Development.
Journal: Pharmaceutical research
Published: January 27, 2022
Potential and Limits of Kidney Cells for Evaluation of Renal Excretion.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: April 25, 2021
Extension of the Mechanistic Tissue Distribution Model of Rodgers and Rowland by Systematic Incorporation of Lysosomal Trapping: Impact on Unbound Partition Coefficient and Volume of Distribution Predictions in the Rat.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: June 26, 2020
Concentration Dependence of the Unbound Partition Coefficient Kpuu and Its Application to Correct for Exposure-Related Discrepancies between Biochemical and Cellular Potency of KAT6A Inhibitors.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: January 31, 2020
Clinical Recommendations for the Use of the Ambulatory Glucose Profile in Diabetes Care.
Journal: Journal of diabetes science and technology
Published: November 14, 2019
Last Updated: 09/26/2026