Andrew G. Purkiss

1 Midland Road, U.K
London, ENG NW11AT, United Kingdom

Last Updated: 09/26/2026

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Found 29 publications

Binding of 14-3-3 stabilises recombinant AMPKγ2-containing complexes.

Binding of 14-3-3 stabilises recombinant AMPKγ2-containing complexes.

Journal: The Biochemical journal

Published: December 10, 2025

Binding of 14-3-3 stabilises recombinant AMPKγ2-containing complexes.

Binding of 14-3-3 stabilises recombinant AMPKγ2-containing complexes.

Journal: The Biochemical journal

Published: December 10, 2025

A Synergistic Inhibitor Development Strategy Against Human UDP-Galactose-4-Epimerase.

A Synergistic Inhibitor Development Strategy Against Human UDP-Galactose-4-Epimerase.

Journal: Angewandte Chemie (International ed. in English)

Published: September 15, 2025

Structural Plasticity of Plasmodium falciparum Plasmepsin X to Accommodate Binding of Potent Macrocyclic Hydroxyethylamine Inhibitors.

Structural Plasticity of Plasmodium falciparum Plasmepsin X to Accommodate Binding of Potent Macrocyclic Hydroxyethylamine Inhibitors.

Journal: Journal of molecular biology

Published: January 09, 2025

Structural and functional characterization of the extended-diKH domain from the antiviral endoribonuclease KHNYN.

Structural and functional characterization of the extended-diKH domain from the antiviral endoribonuclease KHNYN.

Journal: The Journal of biological chemistry

Published: December 23, 2024

The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound.

The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound.

Journal: Nature microbiology

Published: March 19, 2024

Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1.

Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1.

Journal: Nature communications

Published: August 23, 2023

Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly.

Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly.

Journal: Nature communications

Published: April 19, 2023

CCP4 Cloud for structure determination and project management in macromolecular crystallography.

CCP4 Cloud for structure determination and project management in macromolecular crystallography.

Journal: Acta crystallographica. Section D, Structural biology

Published: May 18, 2022

Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of Rp- and Sp-dNTPαS Diastereomers.

Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of Rp- and Sp-dNTPαS Diastereomers.

Journal: Biochemistry

Published: May 14, 2021

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing.

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing.

Journal: Structure (London, England : 1993)

Published: October 13, 2020

Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization.

Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization.

Journal: eLife

Published: September 28, 2020

Showing 1-12 of 29

Last Updated: 09/26/2026