Andrew J. Aguirre

Oncology

450 Brookline Ave
Boston, MA 02215

Last Updated: 09/26/2026

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Found 129 publications

Iron overload suppresses LKB1 and induces IL36G anti-tumor immunity in PDAC metastasis.

Iron overload suppresses LKB1 and induces IL36G anti-tumor immunity in PDAC metastasis.

Journal: Science advances

Published: July 17, 2026

Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.

Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.

Journal: Cell reports

Published: June 17, 2026

Characterization and therapeutic suppression of KEAP1-NRF2-driven resistance to KRAS inhibitors in pancreatic and lung cancer.

Characterization and therapeutic suppression of KEAP1-NRF2-driven resistance to KRAS inhibitors in pancreatic and lung cancer.

Journal: bioRxiv : the preprint server for biology

Published: May 04, 2026

Cell-free chromatin epigenomic profiling enables non-invasive pancreatic cancer cell-state identification.

Cell-free chromatin epigenomic profiling enables non-invasive pancreatic cancer cell-state identification.

Journal: medRxiv : the preprint server for health sciences

Published: April 20, 2026

Growth factor supportive care for chemotherapy-induced neutropenia suppresses antitumour immunity in checkpoint blockade-responsive pancreatic cancer.

Growth factor supportive care for chemotherapy-induced neutropenia suppresses antitumour immunity in checkpoint blockade-responsive pancreatic cancer.

Journal: Immunotherapy advances

Published: April 09, 2026

Integrated inference of cancer gene expression from cell-free plasma chromatin.

Integrated inference of cancer gene expression from cell-free plasma chromatin.

Journal: bioRxiv : the preprint server for biology

Published: February 27, 2026

Integrated inference of cancer gene expression from cell-free plasma chromatin.

Integrated inference of cancer gene expression from cell-free plasma chromatin.

Journal: bioRxiv : the preprint server for biology

Published: February 27, 2026

Cancers modulate p53 truncal neoantigen display to evade T cell detection.

Cancers modulate p53 truncal neoantigen display to evade T cell detection.

Journal: bioRxiv : the preprint server for biology

Published: December 15, 2025

Acquired resistance to the RAS(ON) multi-selective inhibitor daraxonrasib guides rational combination therapy strategies in pancreatic cancer.

Acquired resistance to the RAS(ON) multi-selective inhibitor daraxonrasib guides rational combination therapy strategies in pancreatic cancer.

Journal: Nature medicine

Published: November 25, 2025

VEGFR2 blockade overcomes acquired KRAS G12D inhibitor resistance driven by PI3Kγ activation.

VEGFR2 blockade overcomes acquired KRAS G12D inhibitor resistance driven by PI3Kγ activation.

Journal: bioRxiv : the preprint server for biology

Published: September 26, 2025

Erratum: PASS-01: Randomized Phase II Trial of Modified FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel and Molecular Correlatives for Previously Untreated Metastatic Pancreatic Cancer.

Erratum: PASS-01: Randomized Phase II Trial of Modified FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel and Molecular Correlatives for Previously Untreated Metastatic Pancreatic Cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Published: September 24, 2025

GLIS3 marks a neural-like progenitor cell state that drives metastasis in pancreatic ductal adenocarcinoma.

GLIS3 marks a neural-like progenitor cell state that drives metastasis in pancreatic ductal adenocarcinoma.

Journal: Cell reports

Published: September 18, 2025

Showing 1-12 of 129

Last Updated: 09/26/2026