Andrew M. Thompson
Auckland, AUK 1142, New Zealand
Last Updated: 09/26/2026
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Found 26 publications
New antitubercular pretomanid analogues as potent payloads in polymeric micelles: Leveraging zebrafish assays to accelerate lead optimisation.
Journal: European journal of medicinal chemistry
Published: November 17, 2025
Advancing the antituberculosis activity of nitropicolinic acids and amides.
Journal: European journal of medicinal chemistry
Published: May 22, 2025
Synthesis and Anti-Mycobacterium tuberculosis Activity of Imidazo[2,1-b][1,3]oxazine Derivatives against Multidrug-Resistant Strains.
Journal: ChemMedChem
Published: January 13, 2023
Π-Π interactions stabilize PeptoMicelle-based formulations of Pretomanid derivatives leading to promising therapy against tuberculosis in zebrafish and mouse models.
Journal: Journal of controlled release : official journal of the Controlled Release Society
Published: August 30, 2022
Tuberculosis Drug Discovery: Challenges and New Horizons.
Journal: Journal of medicinal chemistry
Published: May 25, 2022
Novel Linker Variants of Antileishmanial/Antitubercular 7-Substituted 2-Nitroimidazooxazines Offer Enhanced Solubility.
Journal: ACS medicinal chemistry letters
Published: December 12, 2020
Heteroaryl ether analogues of an antileishmanial 7-substituted 2-nitroimidazooxazine lead afford attenuated hERG risk: In vitro and in vivo appraisal.
Journal: European journal of medicinal chemistry
Published: July 15, 2020
Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacy.
Journal: European journal of medicinal chemistry
Published: June 21, 2020
Otago Glaucoma Surgery Outcome Study: Examining the Development of Strabismus Causing Diplopia in Patients Who Have Received Molteno Implant Surgery.
Journal: Journal of binocular vision and ocular motility
Published: March 19, 2020
Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis.
Journal: Journal of medicinal chemistry
Published: February 21, 2018
Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid.
Journal: ACS medicinal chemistry letters
Published: August 28, 2017
Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.
Journal: Bioorganic & medicinal chemistry letters
Published: August 23, 2017
Last Updated: 09/26/2026