Andrew R. Castle
Oxford, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 12 publications
α-Synuclein blocks endoplasmic reticulum co-translational protein translocation early in Parkinson's disease.
Journal: Nature communications
Published: October 05, 2025
Prion Protein Endoproteolysis: Cleavage Sites, Mechanisms and Connections to Prion Disease.
Journal: Journal of neurochemistry
Published: November 29, 2024
Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson's disease.
Journal: Cell reports. Medicine
Published: October 10, 2024
Beta-endoproteolysis of the cellular prion protein by dipeptidyl peptidase-4 and fibroblast activation protein.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: December 27, 2022
Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles.
Journal: PloS one
Published: March 27, 2022
Prion protein with a mutant N-terminal octarepeat region undergoes cobalamin-dependent assembly into high-molecular weight complexes.
Journal: The Journal of biological chemistry
Published: December 22, 2021
Application of high-throughput, capillary-based Western analysis to modulated cleavage of the cellular prion protein.
Journal: The Journal of biological chemistry
Published: October 22, 2018
The cellular and pathologic prion protein.
Journal: Handbook of clinical neurology
Published: June 12, 2018
Physiological Functions of the Cellular Prion Protein.
Journal: Frontiers in molecular biosciences
Published: February 20, 2017
Natural history of retinopathy in children and young people with type 1 diabetes.
Journal: Eye (London, England)
Published: July 26, 2015
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Last Updated: 09/26/2026