Andrew R. Osborne

Norwich, ENG NR47GJ, United Kingdom

Last Updated: 09/26/2026

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Found 43 publications

Gene-Agnostic Therapeutic Strategies for Inherited Retinal Diseases: Neuroprotection and Immunomodulation.

Gene-Agnostic Therapeutic Strategies for Inherited Retinal Diseases: Neuroprotection and Immunomodulation.

Journal: Genes
Published: January 01, 2026

TrkB Overexpression via Gene Therapy: Enhanced Optic Nerve Uptake With Associated Increases in Mitochondria and Axoplasmic Transport.

TrkB Overexpression via Gene Therapy: Enhanced Optic Nerve Uptake With Associated Increases in Mitochondria and Axoplasmic Transport.

Journal: Cureus
Published: December 29, 2025

Dose-ranging and further therapeutic evaluation of a bicistronic humanized TrkB-BDNF gene therapy for glaucoma in rodents.

Dose-ranging and further therapeutic evaluation of a bicistronic humanized TrkB-BDNF gene therapy for glaucoma in rodents.

Journal: Molecular neurodegeneration advances
Published: July 21, 2025

Ocular delivery of Pigment Epithelium-Derived Factor (PEDF) as a neuroprotectant for Geographic Atrophy.

Ocular delivery of Pigment Epithelium-Derived Factor (PEDF) as a neuroprotectant for Geographic Atrophy.

Journal: Aging and disease
Published: December 21, 2023

Intravitreal Injection of AAV for the Transduction of Mouse Retinal Ganglion Cells.

Intravitreal Injection of AAV for the Transduction of Mouse Retinal Ganglion Cells.

Journal: Methods in molecular biology (Clifton, N.J.)
Published: August 09, 2023

Predictors of in-hospital mortality in critically ill patients with COVID-19: a large dual tertiary centre study.

Predictors of in-hospital mortality in critically ill patients with COVID-19: a large dual tertiary centre study.

Journal: BMJ open
Published: December 01, 2022

Formation of ER-lumenal intermediates during export of Plasmodium proteins containing transmembrane-like hydrophobic sequences.

Formation of ER-lumenal intermediates during export of Plasmodium proteins containing transmembrane-like hydrophobic sequences.

Journal: PLoS pathogens
Published: September 24, 2022

Immunobiology of a rationally-designed AAV2 capsid following intravitreal delivery in mice.

Immunobiology of a rationally-designed AAV2 capsid following intravitreal delivery in mice.

Journal: Gene therapy
Published: August 23, 2022

Therapeutic Potential of Astrocyte Transplantation.

Therapeutic Potential of Astrocyte Transplantation.

Journal: Cell transplantation
Published: June 30, 2022

Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters.

Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters.

Journal: Gene therapy
Published: April 19, 2022

Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1.

Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1.

Journal: eLife
Published: August 05, 2021

Quantifying inter-organelle membrane contact sites using proximity ligation assay in fixed optic nerve sections.

Quantifying inter-organelle membrane contact sites using proximity ligation assay in fixed optic nerve sections.

Journal: Experimental eye research
Published: June 28, 2021
Showing 1-12 of 43

Last Updated: 09/26/2026