Andy T. Merritt

Mill Hill
London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 20 publications

Formation of mono- and dual-labelled antibody fragment conjugates via reversible site-selective disulfide modification and proximity induced lysine reactivity.

Formation of mono- and dual-labelled antibody fragment conjugates via reversible site-selective disulfide modification and proximity induced lysine reactivity.

Journal: Chemical science

Published: October 04, 2024

Fragment Merging Using a Graph Database Samples Different Catalogue Space than Similarity Search.

Fragment Merging Using a Graph Database Samples Different Catalogue Space than Similarity Search.

Journal: Journal of chemical information and modeling

Published: May 25, 2023

Identification and characterisation of anti-IL-13 inhibitory single domain antibodies provides new insights into receptor selectivity and attractive opportunities for drug discovery.

Identification and characterisation of anti-IL-13 inhibitory single domain antibodies provides new insights into receptor selectivity and attractive opportunities for drug discovery.

Journal: Frontiers in immunology

Published: May 04, 2023

Incorporating Target-Specific Pharmacophoric Information into Deep Generative Models for Fragment Elaboration.

Incorporating Target-Specific Pharmacophoric Information into Deep Generative Models for Fragment Elaboration.

Journal: Journal of chemical information and modeling

Published: May 02, 2022

Identification and characterization of bisbenzimide compounds that inhibit human cytomegalovirus replication.

Identification and characterization of bisbenzimide compounds that inhibit human cytomegalovirus replication.

Journal: The Journal of general virology

Published: December 09, 2021

Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists.

Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists.

Journal: European journal of medicinal chemistry

Published: April 09, 2021

Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase.

Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase.

Journal: ACS infectious diseases

Published: December 09, 2020

Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation.

Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation.

Journal: European journal of medicinal chemistry

Published: November 17, 2020

Fragment-based target screening as an empirical approach to prioritising targets: a case study on antibacterials.

Fragment-based target screening as an empirical approach to prioritising targets: a case study on antibacterials.

Journal: Drug discovery today

Published: January 22, 2020

Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty.

Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty.

Journal: Bioorganic & medicinal chemistry letters

Published: July 01, 2019

Developing an Antibody-Drug Conjugate Approach to Selective Inhibition of an Extracellular Protein.

Developing an Antibody-Drug Conjugate Approach to Selective Inhibition of an Extracellular Protein.

Journal: Chembiochem : a European journal of chemical biology

Published: October 15, 2018

Design of the LifeArc Index Set and Retrospective Review of Its Performance: A Collection for Sharing.

Design of the LifeArc Index Set and Retrospective Review of Its Performance: A Collection for Sharing.

Journal: SLAS discovery : advancing life sciences R & D

Published: October 06, 2018

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Last Updated: 09/26/2026