Andy Y. Lo - Publications

Mechanisms of pulmonary arterial hypertension-induced atrial fibrillation: insights from multi-scale models of the human atria.

Journal: Interface focus

Published: August 16, 2023

Mechanisms underlying pro-arrhythmic abnormalities arising from Pitx2-induced electrical remodelling: an in silico intersubject variability study.

Journal: Annals of translational medicine

Published: February 11, 2021

In Silico Assessment of Class I Antiarrhythmic Drug Effects on Pitx2-Induced Atrial Fibrillation: Insights from Populations of Electrophysiological Models of Human Atrial Cells and Tissues.

Journal: International journal of molecular sciences

Published: November 23, 2020

In Silico Assessment of Genetic Variation in PITX2 Reveals the Molecular Mechanisms of Calcium-Mediated Cellular Triggered Activity in Atrial Fibrillation.

Journal: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Published: October 06, 2020

Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a sensitivity analysis of calcium handling channels.

Journal: Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

Published: May 26, 2020

PITX2 upregulation increases the risk of chronic atrial fibrillation in a dose-dependent manner by modulating IKs and ICaL -insights from human atrial modelling.

Journal: Annals of translational medicine

Published: April 21, 2020

In silico investigation of the mechanisms underlying atrial fibrillation due to impaired Pitx2.

Journal: PLoS computational biology

Published: July 04, 2019

Proarrhythmia in the p.Met207Val PITX2c-Linked Familial Atrial Fibrillation-Insights From Modeling.

Journal: Frontiers in physiology

Published: June 26, 2019