Angel L. Pey

Granada, AN 18071, Spain

Last Updated: 09/26/2026

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Found 82 publications

Targeting Oxalate Production by Combining Enzyme Inhibition and Proteolysis Activation: A Novel Therapeutic Approach for Primary Hyperoxaluria Type 1.

Targeting Oxalate Production by Combining Enzyme Inhibition and Proteolysis Activation: A Novel Therapeutic Approach for Primary Hyperoxaluria Type 1.

Journal: Journal of medicinal chemistry

Published: January 02, 2026

Minimized sample consumption for time-resolved serial crystallography applied to the redox cycle of human NQO1.

Minimized sample consumption for time-resolved serial crystallography applied to the redox cycle of human NQO1.

Journal: Communications chemistry

Published: November 11, 2025

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry.

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry.

Journal: The FEBS journal

Published: October 20, 2025

Impact of Ser81 phosphorylation on alanine: glyoxylate aminotransferase associated with Primary hyperoxaluria type I.

Impact of Ser81 phosphorylation on alanine: glyoxylate aminotransferase associated with Primary hyperoxaluria type I.

Journal: Molecular biomedicine

Published: June 23, 2025

Nanobodies as therapies for loss-of-function misfolding diseases: the example of Primary Hyperoxaluria Type 1.

Nanobodies as therapies for loss-of-function misfolding diseases: the example of Primary Hyperoxaluria Type 1.

Journal: International journal of biological macromolecules

Published: May 09, 2025

The lack of trade-off between conformational stability and binding affinity in a nanobody with therapeutic potential for a misfolding disease.

The lack of trade-off between conformational stability and binding affinity in a nanobody with therapeutic potential for a misfolding disease.

Journal: International journal of biological macromolecules

Published: September 22, 2024

Thermodynamic versus kinetic basis for the high conformational stability of nanobodies for therapeutic applications.

Thermodynamic versus kinetic basis for the high conformational stability of nanobodies for therapeutic applications.

Journal: FEBS letters

Published: August 29, 2024

Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations.

Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations.

Journal: Protein science : a publication of the Protein Society

Published: December 21, 2023

Phosphorylation of cytosolic hPGK1 affects protein stability and ligand binding: implications for its subcellular targeting in cancer.

Phosphorylation of cytosolic hPGK1 affects protein stability and ligand binding: implications for its subcellular targeting in cancer.

Journal: The FEBS journal

Published: October 27, 2023

Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants.

Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants.

Journal: FEBS letters

Published: October 13, 2023

Structural dynamics at the active site of the cancer-associated flavoenzyme NQO1 probed by chemical modification with PMSF.

Structural dynamics at the active site of the cancer-associated flavoenzyme NQO1 probed by chemical modification with PMSF.

Journal: FEBS letters

Published: July 05, 2023

Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme.

Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme.

Journal: Lab on a chip

Published: June 09, 2023

Showing 1-12 of 82

Last Updated: 09/26/2026