Angelo Pugliese

Bo'Ness Rd, Chapelhall
Motherwell, SCT ML15UH, United Kingdom

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 8 publications

Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras.

Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras.

Journal: Journal of medicinal chemistry

Published: March 31, 2025

Discovery and characterization of novel TRPML1 agonists.

Discovery and characterization of novel TRPML1 agonists.

Journal: Bioorganic & medicinal chemistry letters

Published: October 05, 2023

Implementation of an AI-assisted fragment-generator in an open-source platform.

Implementation of an AI-assisted fragment-generator in an open-source platform.

Journal: RSC medicinal chemistry

Published: May 20, 2022

Stabilization of the RAS:PDE6D Complex Is a Novel Strategy to Inhibit RAS Signaling.

Stabilization of the RAS:PDE6D Complex Is a Novel Strategy to Inhibit RAS Signaling.

Journal: Journal of medicinal chemistry

Published: February 02, 2022

Automated Generation of Novel Fragments Using Screening Data, a Dual SMILES Autoencoder, Transfer Learning and Syntax Correction.

Automated Generation of Novel Fragments Using Screening Data, a Dual SMILES Autoencoder, Transfer Learning and Syntax Correction.

Journal: Journal of chemical information and modeling

Published: May 24, 2021

Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.

Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.

Journal: Bioorganic & medicinal chemistry letters

Published: November 26, 2018

Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks.

Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks.

Journal: Neoplasia (New York, N.Y.)

Published: April 02, 2015

Fragment-based hit identification: thinking in 3D.

Fragment-based hit identification: thinking in 3D.

Journal: Drug discovery today

Published: May 16, 2013

Showing 1-8 of 8

Last Updated: 09/26/2026