Anirudha Lakshminarasimhan

NCBS Campus, Bellary Road
Bengaluru, KA 560065, India

Last Updated: 09/26/2026

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Found 9 publications

Sofosbuvir and its tri-phosphate metabolite inhibit the RNA-dependent RNA polymerase activity of non-structural protein 5 from the Kyasanur forest disease virus.

Sofosbuvir and its tri-phosphate metabolite inhibit the RNA-dependent RNA polymerase activity of non-structural protein 5 from the Kyasanur forest disease virus.

Journal: Biochemical and biophysical research communications

Published: November 29, 2022

Refolding and characterization of a diabody against Pfs25, a vaccine candidate of Plasmodium falciparum.

Refolding and characterization of a diabody against Pfs25, a vaccine candidate of Plasmodium falciparum.

Journal: Analytical biochemistry

Published: February 27, 2022

Plasmodium chitinases: revisiting a target of transmission-blockade against malaria.

Plasmodium chitinases: revisiting a target of transmission-blockade against malaria.

Journal: Protein science : a publication of the Protein Society

Published: March 09, 2021

PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy.

PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy.

Journal: Communications biology

Published: August 19, 2020

Ternary complex formation of AFN-1252 with Acinetobacter baumannii FabI and NADH: Crystallographic and biochemical studies.

Ternary complex formation of AFN-1252 with Acinetobacter baumannii FabI and NADH: Crystallographic and biochemical studies.

Journal: Chemical biology & drug design

Published: July 30, 2019

Structure-guided discovery of 2-aryl/pyridin-2-yl-1H-indole derivatives as potent and selective hepsin inhibitors.

Structure-guided discovery of 2-aryl/pyridin-2-yl-1H-indole derivatives as potent and selective hepsin inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: July 07, 2015

AFN-1252 is a potent inhibitor of enoyl-ACP reductase from Burkholderia pseudomallei--Crystal structure, mode of action, and biological activity.

AFN-1252 is a potent inhibitor of enoyl-ACP reductase from Burkholderia pseudomallei--Crystal structure, mode of action, and biological activity.

Journal: Protein science : a publication of the Protein Society

Published: November 06, 2014

Discovery of azetidine based ene-amides as potent bacterial enoyl ACP reductase (FabI) inhibitors.

Discovery of azetidine based ene-amides as potent bacterial enoyl ACP reductase (FabI) inhibitors.

Journal: European journal of medicinal chemistry

Published: January 31, 2014

Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode.

Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode.

Journal: Bioorganic & medicinal chemistry letters

Published: March 21, 2013

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Last Updated: 09/26/2026