Anna H. Hirsch

Carl Neuberg Str. 1
Hannover, NI 30625, Germany

Last Updated: 09/26/2026

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Found 186 publications

Targeting the Energy-Coupling Factor Transporters: A Novel Antibiotic Drug Target in Streptococcus pneumoniae.

Targeting the Energy-Coupling Factor Transporters: A Novel Antibiotic Drug Target in Streptococcus pneumoniae.

Journal: Journal of medicinal chemistry

Published: June 12, 2026

Hit-to-Lead Optimization of Energy-Coupling Factor (ECF) Transporter Inhibitors as Novel Antibiotic.

Hit-to-Lead Optimization of Energy-Coupling Factor (ECF) Transporter Inhibitors as Novel Antibiotic.

Journal: Journal of medicinal chemistry

Published: June 06, 2026

Cytochrome P450-Mediated Metabolism of Antimycobacterial Nα-Aroyl-N-aryl-phenylalanine Amides.

Cytochrome P450-Mediated Metabolism of Antimycobacterial Nα-Aroyl-N-aryl-phenylalanine Amides.

Journal: ACS infectious diseases

Published: June 02, 2026

Identification of DksA as a novel pro-inflammatory mediator of Pseudomonas aeruginosa under conditions mimicking chronic cystic fibrosis lung infection.

Identification of DksA as a novel pro-inflammatory mediator of Pseudomonas aeruginosa under conditions mimicking chronic cystic fibrosis lung infection.

Journal: Virulence

Published: May 12, 2026

A new bactericidal thiourea antibiotic against drug-resistant Staphylococcus aureus with in vivo activity and no detectable resistance.

A new bactericidal thiourea antibiotic against drug-resistant Staphylococcus aureus with in vivo activity and no detectable resistance.

Journal: European journal of medicinal chemistry

Published: April 23, 2026

X-ray Co-crystal Structure of a Novel Pseudomonas aeruginosa DXPS Inhibitor Reveals an Unusual Allosteric Binding Pocket.

X-ray Co-crystal Structure of a Novel Pseudomonas aeruginosa DXPS Inhibitor Reveals an Unusual Allosteric Binding Pocket.

Journal: Research square

Published: April 17, 2026

Exploring the Role of Pseudomonas aeruginosa Elastase in Lung Epithelial Barrier Dysfunction: Advancing toward Antivirulence Therapies.

Exploring the Role of Pseudomonas aeruginosa Elastase in Lung Epithelial Barrier Dysfunction: Advancing toward Antivirulence Therapies.

Journal: ACS infectious diseases

Published: April 10, 2026

Data driven selection of consensus docking pipelines for structure based hit identification.

Data driven selection of consensus docking pipelines for structure based hit identification.

Journal: npj drug discovery

Published: April 02, 2026

Genome Mining Guided Identification of the Metallophore Delftichelin A from Delftia deserti.

Genome Mining Guided Identification of the Metallophore Delftichelin A from Delftia deserti.

Journal: Journal of natural products

Published: March 27, 2026

Design of Poly-Catechol Biodynamers for Potentiation of Antibiotic Efficacy against Drug-Resistant Bacteria.

Design of Poly-Catechol Biodynamers for Potentiation of Antibiotic Efficacy against Drug-Resistant Bacteria.

Journal: Biomacromolecules

Published: February 23, 2026

Multiparameter Optimization of Pseudomonas aeruginosa Elastase Inhibitors for Systemic Administration.

Multiparameter Optimization of Pseudomonas aeruginosa Elastase Inhibitors for Systemic Administration.

Journal: Journal of medicinal chemistry

Published: February 05, 2026

Identification of Natural-Product Inhibitors of the 2C‑Methyl‑d‑erythritol 4‑Phosphate Pathway.

Identification of Natural-Product Inhibitors of the 2C‑Methyl‑d‑erythritol 4‑Phosphate Pathway.

Journal: ACS medicinal chemistry letters

Published: January 25, 2026

Showing 1-12 of 186

Last Updated: 09/26/2026