Annabel Leon-Garcia

Barcelona, CT 08041, Spain

Last Updated: 09/26/2026

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Found 16 publications

Precision targeting of CXCR4+ leukemia cells by a humanized MMAE-nanoconjugate in an AML mouse model.

Precision targeting of CXCR4+ leukemia cells by a humanized MMAE-nanoconjugate in an AML mouse model.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: July 15, 2025

Conjugation strategy shapes antitumor efficacy and enables dose-sparing in non-antibody protein nanoconjugates.

Conjugation strategy shapes antitumor efficacy and enables dose-sparing in non-antibody protein nanoconjugates.

Journal: Materials today. Bio
Published: June 19, 2025

Paradoxical cell targeting of calreticulin-empowered, protein-only nanoparticles.

Paradoxical cell targeting of calreticulin-empowered, protein-only nanoparticles.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Published: April 26, 2024

T22-PE24-H6 Nanotoxin Selectively Kills CXCR4-High Expressing AML Patient Cells In Vitro and Potently Blocks Dissemination In Vivo.

T22-PE24-H6 Nanotoxin Selectively Kills CXCR4-High Expressing AML Patient Cells In Vitro and Potently Blocks Dissemination In Vivo.

Journal: Pharmaceutics
Published: January 31, 2023

Potent Anticancer Activity of CXCR4-Targeted Nanostructured Toxins in Aggressive Endometrial Cancer Models.

Potent Anticancer Activity of CXCR4-Targeted Nanostructured Toxins in Aggressive Endometrial Cancer Models.

Journal: Cancers
Published: December 05, 2022

A diphtheria toxin-based nanoparticle achieves specific cytotoxic effect on CXCR4+ lymphoma cells without toxicity in immunocompromised and immunocompetent mice.

A diphtheria toxin-based nanoparticle achieves specific cytotoxic effect on CXCR4+ lymphoma cells without toxicity in immunocompromised and immunocompetent mice.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: February 21, 2022

Time-Prolonged Release of Tumor-Targeted Protein-MMAE Nanoconjugates from Implantable Hybrid Materials.

Time-Prolonged Release of Tumor-Targeted Protein-MMAE Nanoconjugates from Implantable Hybrid Materials.

Journal: Pharmaceutics
Published: December 15, 2021

Engineering non-antibody human proteins as efficient scaffolds for selective, receptor-targeted drug delivery.

Engineering non-antibody human proteins as efficient scaffolds for selective, receptor-targeted drug delivery.

Journal: Journal of controlled release : official journal of the Controlled Release Society
Published: October 01, 2021

A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model.

A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model.

Journal: Biomaterials
Published: May 26, 2021

LDL Receptor Regulates the Reverse Transport of Macrophage-Derived Unesterified Cholesterol via Concerted Action of the HDL-LDL Axis: Insight From Mouse Models.

LDL Receptor Regulates the Reverse Transport of Macrophage-Derived Unesterified Cholesterol via Concerted Action of the HDL-LDL Axis: Insight From Mouse Models.

Journal: Circulation research
Published: June 05, 2020

Cholesterol and 27-hydroxycholesterol promote thyroid carcinoma aggressiveness.

Cholesterol and 27-hydroxycholesterol promote thyroid carcinoma aggressiveness.

Journal: Scientific reports
Published: January 24, 2019

Impaired HDL (High-Density Lipoprotein)-Mediated Macrophage Cholesterol Efflux in Patients With Abdominal Aortic Aneurysm-Brief Report.

Impaired HDL (High-Density Lipoprotein)-Mediated Macrophage Cholesterol Efflux in Patients With Abdominal Aortic Aneurysm-Brief Report.

Journal: Arteriosclerosis, thrombosis, and vascular biology
Published: October 26, 2018
Showing 1-12 of 16

Last Updated: 09/26/2026