Anne T. Nies

Dr. Margarete Fischer Bosch Institute Of Clinical Pharmacology
Tuebingen, BW, Germany

Last Updated: 09/26/2026

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Found 56 publications

Mechanistically resolved prediction of compound hepatotoxicity using primary human liver spheroids-Application to recent real-world cases.

Mechanistically resolved prediction of compound hepatotoxicity using primary human liver spheroids-Application to recent real-world cases.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: April 22, 2026

Identification of Brimonidine as a Novel Substrate of Organic Cation Transporters OCT2 and MATE1 Expressed in Human Eye.

Identification of Brimonidine as a Novel Substrate of Organic Cation Transporters OCT2 and MATE1 Expressed in Human Eye.

Journal: Investigative ophthalmology & visual science

Published: April 02, 2026

Feed-Forward Deep Neural Networks Predict Substrate-Specific Effects of Transporter Variants to Explain Drug Response Variability.

Feed-Forward Deep Neural Networks Predict Substrate-Specific Effects of Transporter Variants to Explain Drug Response Variability.

Journal: Clinical and translational science

Published: January 08, 2026

Humanized Fruit Flies as a Novel Pre-Clinical Test Model for Membrane Drug Transporters.

Humanized Fruit Flies as a Novel Pre-Clinical Test Model for Membrane Drug Transporters.

Journal: Frontiers in bioscience (Landmark edition)

Published: February 14, 2025

In silico and biological analyses of missense variants of the human biliary efflux transporter ABCC2: effects of novel rare missense variants.

In silico and biological analyses of missense variants of the human biliary efflux transporter ABCC2: effects of novel rare missense variants.

Journal: British journal of pharmacology

Published: March 11, 2024

Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation.

Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation.

Journal: Pharmacological research

Published: August 14, 2023

Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation.

Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation.

Journal: International journal of molecular sciences

Published: June 10, 2022

Hepatic solute carrier transporters and drug therapy: Regulation of expression and impact of genetic variation.

Hepatic solute carrier transporters and drug therapy: Regulation of expression and impact of genetic variation.

Journal: Pharmacology & therapeutics

Published: June 03, 2022

Raman Imaging and Fluorescence Lifetime Imaging Microscopy for Diagnosis of Cancer State and Metabolic Monitoring.

Raman Imaging and Fluorescence Lifetime Imaging Microscopy for Diagnosis of Cancer State and Metabolic Monitoring.

Journal: Cancers

Published: September 29, 2021

Genetic and Epigenetic Regulation of Organic Cation Transporters.

Genetic and Epigenetic Regulation of Organic Cation Transporters.

Journal: Handbook of experimental pharmacology

Published: March 06, 2021

Interaction of Remdesivir with Clinically Relevant Hepatic Drug Uptake Transporters.

Interaction of Remdesivir with Clinically Relevant Hepatic Drug Uptake Transporters.

Journal: Pharmaceutics

Published: February 08, 2021

Effects of a Common Eight Base Pairs Duplication at the Exon 7-Intron 7 Junction on Splicing, Expression, and Function of OCT1.

Effects of a Common Eight Base Pairs Duplication at the Exon 7-Intron 7 Junction on Splicing, Expression, and Function of OCT1.

Journal: Frontiers in pharmacology

Published: February 01, 2021

Showing 1-12 of 56

Last Updated: 09/26/2026