Annukka S. Jouppila
Helsinki, Finland
Last Updated: 09/26/2026
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Found 26 publications
Therapeutic Strategies Combining Antiplatelet With Anticoagulant Actions: Heparin Proteoglycan Mimetic APAC as a Model.
Journal: Arteriosclerosis, thrombosis, and vascular biology
Published: May 28, 2026
Interactions of dual antiplatelet and anticoagulant with C1q and FH regulate complement activation by injured cells.
Journal: Blood vessels, thrombosis & hemostasis
Published: July 11, 2025
Escalating doses of intravenous APAC demonstrate antithrombotic effect in pigs.
Journal: Thrombosis journal
Published: March 04, 2025
Antiplatelet-anticoagulant, APAC, a mimic of endogenous heparin, is an antithrombotic with von Willebrand factor-mediated characteristics.
Journal: Thrombosis research
Published: December 04, 2024
Heparin-like effect of a dual antiplatelet and anticoagulant (APAC) agent on red blood cell deformability and aggregation in an experimental model.
Journal: Journal of thrombosis and thrombolysis
Published: August 25, 2024
Treatment with APAC, a dual antiplatelet anticoagulant heparin proteoglycan mimetic, limits early collar-induced carotid atherosclerotic plaque development in Apoe-/- mice.
Journal: Atherosclerosis
Published: March 24, 2024
Pretreatment with a dual antiplatelet and anticoagulant (APAC) reduces ischemia-reperfusion injury in a mouse model of temporary middle cerebral artery occlusion-implications for neurovascular procedures.
Journal: Acta neurochirurgica
Published: December 05, 2023
Intravenously administered APAC, a dual AntiPlatelet AntiCoagulant, targets arterial injury site to inhibit platelet thrombus formation and tissue factor activity in mice.
Journal: Thrombosis research
Published: December 08, 2022
Urinary extracellular vesicles carry multiple activators and regulators of coagulation.
Journal: Frontiers in cell and developmental biology
Published: June 12, 2022
Thrombosis and Inflammation-A Dynamic Interplay and the Role of Glycosaminoglycans and Activated Protein C.
Journal: Frontiers in cardiovascular medicine
Published: January 31, 2022
AFM investigation of APAC (antiplatelet and anticoagulant heparin proteoglycan).
Journal: Analytical and bioanalytical chemistry
Published: September 13, 2021
COVID-19 adenovirus vaccine triggers antibodies against PF4 complexes to activate complement and platelets.
Journal: Thrombosis research
Published: September 10, 2021
Last Updated: 09/26/2026