Anthony Tumber

Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 97 publications

Structural basis of the promiscuity of the unusual Fe(II) and 2-oxoglutarate dependent human aspartate/asparagine-β-hydroxylase.

Structural basis of the promiscuity of the unusual Fe(II) and 2-oxoglutarate dependent human aspartate/asparagine-β-hydroxylase.

Journal: Nature communications

Published: August 30, 2025

Profiling Inhibitor Scaffolds for the Cancer Target Jumonji-C Domain-Containing Protein 6.

Profiling Inhibitor Scaffolds for the Cancer Target Jumonji-C Domain-Containing Protein 6.

Journal: ChemMedChem

Published: August 07, 2025

Derivatives of the Clinically Used HIF Prolyl Hydroxylase Inhibitor Desidustat Are Efficient Inhibitors of Human γ-Butyrobetaine Hydroxylase.

Derivatives of the Clinically Used HIF Prolyl Hydroxylase Inhibitor Desidustat Are Efficient Inhibitors of Human γ-Butyrobetaine Hydroxylase.

Journal: Journal of medicinal chemistry

Published: April 23, 2025

Investigating the N-terminal linker histone H1 subtypes as substrates for JmjC lysine demethylases.

Investigating the N-terminal linker histone H1 subtypes as substrates for JmjC lysine demethylases.

Journal: RSC chemical biology

Published: April 08, 2025

RaPID discovery of cell-permeable helical peptide inhibitors con-taining cyclic β-amino acids against SARS-CoV-2 main protease.

RaPID discovery of cell-permeable helical peptide inhibitors con-taining cyclic β-amino acids against SARS-CoV-2 main protease.

Journal: RSC chemical biology

Published: February 02, 2025

Biochemical investigations using mass spectrometry to monitor JMJD6-catalysed hydroxylation of multi-lysine containing bromodomain-derived substrates.

Biochemical investigations using mass spectrometry to monitor JMJD6-catalysed hydroxylation of multi-lysine containing bromodomain-derived substrates.

Journal: RSC chemical biology

Published: December 15, 2024

KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9.

KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9.

Journal: Nature chemistry

Published: December 02, 2024

Methods for production and assaying catalysis of isolated recombinant human aspartate/asparagine-β-hydroxylase.

Methods for production and assaying catalysis of isolated recombinant human aspartate/asparagine-β-hydroxylase.

Journal: Methods in enzymology

Published: September 20, 2024

Crystallographic and Selectivity Studies on the Approved HIF Prolyl Hydroxylase Inhibitors Desidustat and Enarodustat.

Crystallographic and Selectivity Studies on the Approved HIF Prolyl Hydroxylase Inhibitors Desidustat and Enarodustat.

Journal: ChemMedChem

Published: July 03, 2024

Substrate selectivity and inhibition of the human lysyl hydroxylase JMJD7.

Substrate selectivity and inhibition of the human lysyl hydroxylase JMJD7.

Journal: Protein science : a publication of the Protein Society

Published: June 11, 2024

A Small-Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine-Flip Pocket for the Treatment of Obesity.

A Small-Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine-Flip Pocket for the Treatment of Obesity.

Journal: Angewandte Chemie (International ed. in English)

Published: June 03, 2024

Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate.

Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate.

Journal: Journal of medicinal chemistry

Published: January 31, 2024

Showing 1-12 of 97

Last Updated: 09/26/2026