Ao Hai

Chengdu, 610041, China

Last Updated: 09/26/2026

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Found 11 publications

Design and Characterization of a Dual COX-2/CaV2.2 Inhibitor with Potent Analgesic Activity.

Design and Characterization of a Dual COX-2/CaV2.2 Inhibitor with Potent Analgesic Activity.

Journal: Journal of medicinal chemistry

Published: January 29, 2026

From target specificity to metabolic efficiency: Design and optimization of etomidate analogues for potential improvement in postoperative outcomes.

From target specificity to metabolic efficiency: Design and optimization of etomidate analogues for potential improvement in postoperative outcomes.

Journal: Acta pharmaceutica Sinica. B

Published: July 02, 2025

A promising novel local anesthetic for effective anesthesia in oral inflammatory conditions through reducing mitochondria-related apoptosis.

A promising novel local anesthetic for effective anesthesia in oral inflammatory conditions through reducing mitochondria-related apoptosis.

Journal: Acta pharmaceutica Sinica. B

Published: October 24, 2024

Molecular Transformers: Adaptive Multitarget Ligands for Esterase-Induced Transition from Analgesics to Anesthetics.

Molecular Transformers: Adaptive Multitarget Ligands for Esterase-Induced Transition from Analgesics to Anesthetics.

Journal: Journal of medicinal chemistry

Published: July 16, 2024

Identification of the first selective bioluminescent probe for real-time monitoring of carboxylesterase 2 in vitro and in vivo.

Identification of the first selective bioluminescent probe for real-time monitoring of carboxylesterase 2 in vitro and in vivo.

Journal: The Analyst

Published: December 11, 2023

A Novel Bifunctional μOR Agonist and σ1R Antagonist with Potent Analgesic Responses and Reduced Adverse Effects.

A Novel Bifunctional μOR Agonist and σ1R Antagonist with Potent Analgesic Responses and Reduced Adverse Effects.

Journal: Journal of medicinal chemistry

Published: November 28, 2023

Deep simulated annealing for the discovery of novel dental anesthetics with local anesthesia and anti-inflammatory properties.

Deep simulated annealing for the discovery of novel dental anesthetics with local anesthesia and anti-inflammatory properties.

Journal: Acta pharmaceutica Sinica. B

Published: November 22, 2023

Corrigendum to "Design, synthesis and biological evaluation of novel procaine derivatives for intravenous anesthesia" [Bioorg. Med. Chem. Lett. 60 (2022) 128587].

Corrigendum to "Design, synthesis and biological evaluation of novel procaine derivatives for intravenous anesthesia" [Bioorg. Med. Chem. Lett. 60 (2022) 128587].

Journal: Bioorganic & medicinal chemistry letters

Published: May 07, 2022

Design, synthesis and biological evaluation of novel procaine derivatives for intravenous anesthesia.

Design, synthesis and biological evaluation of novel procaine derivatives for intravenous anesthesia.

Journal: Bioorganic & medicinal chemistry letters

Published: November 06, 2021

Biological applications of a turn-on bioluminescent probe for monitoring sulfite oxidase deficiency in vivo.

Biological applications of a turn-on bioluminescent probe for monitoring sulfite oxidase deficiency in vivo.

Journal: European journal of medicinal chemistry

Published: January 07, 2020

Bioluminescence imaging of exogenous & endogenous cysteine in vivo with a highly selective probe.

Bioluminescence imaging of exogenous & endogenous cysteine in vivo with a highly selective probe.

Journal: Bioorganic & medicinal chemistry letters

Published: November 08, 2019

Showing 1-11 of 11

Last Updated: 09/26/2026