Ao Zhang

CAS Key Laboratory Of Receptor Research And The State Key Laboratory Of Drug Research
Shanghai, 201203, China

Last Updated: 09/26/2026

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Found 104 publications

Design, synthesis and pharmacological evaluation of new SMARCA2 degraders bearing a furo[3,2-c]pyridazine scaffold.

Design, synthesis and pharmacological evaluation of new SMARCA2 degraders bearing a furo[3,2-c]pyridazine scaffold.

Journal: European journal of medicinal chemistry

Published: December 07, 2025

Identification of an STING inhibitor targeting the allosteric transmembrane domains.

Identification of an STING inhibitor targeting the allosteric transmembrane domains.

Journal: Cell chemical biology

Published: August 26, 2025

Synergistic mineralization of the UV filter benzophenone-3 by a cross-feeding consortium from wastewater treatment plants: Insights into novel pathway and bioremediation strategy.

Synergistic mineralization of the UV filter benzophenone-3 by a cross-feeding consortium from wastewater treatment plants: Insights into novel pathway and bioremediation strategy.

Journal: Journal of hazardous materials

Published: August 04, 2025

Zhenqi Fuzheng Granule targets the SCFAs-GPR109A axis to enhance PD-1 antibody efficacy via immunometabolic remodeling in colorectal cancer.

Zhenqi Fuzheng Granule targets the SCFAs-GPR109A axis to enhance PD-1 antibody efficacy via immunometabolic remodeling in colorectal cancer.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: June 30, 2025

Deacetylase SIRT1 modulates antiviral innate immunity and autoimmune diseases.

Deacetylase SIRT1 modulates antiviral innate immunity and autoimmune diseases.

Journal: International journal of biological macromolecules

Published: June 29, 2025

The immunomodulatory roles of endogenous circular RNAs: Biogenesis, function, and therapeutic exploitation.

The immunomodulatory roles of endogenous circular RNAs: Biogenesis, function, and therapeutic exploitation.

Journal: Biochemical pharmacology

Published: April 15, 2025

Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth.

Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth.

Journal: Molecules (Basel, Switzerland)

Published: February 28, 2025

Clinical and functional significance of SPATA2 in cancer particularly in LIHC.

Clinical and functional significance of SPATA2 in cancer particularly in LIHC.

Journal: Scientific reports

Published: November 28, 2024

Synthesis and pharmacological evaluation of natural product diphyllin derivatives against head and neck squamous cell carcinoma.

Synthesis and pharmacological evaluation of natural product diphyllin derivatives against head and neck squamous cell carcinoma.

Journal: European journal of medicinal chemistry

Published: October 26, 2024

Diversified Fluoroalkylation of Alkenes Using Quaternary Fluoroalkyl Alcohols as the Fluoroalkylating Reagents.

Diversified Fluoroalkylation of Alkenes Using Quaternary Fluoroalkyl Alcohols as the Fluoroalkylating Reagents.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: July 29, 2024

PRPS2 enhances RNA m6A methylation by stimulating SAM synthesis through enzyme-dependent and independent mechanisms.

PRPS2 enhances RNA m6A methylation by stimulating SAM synthesis through enzyme-dependent and independent mechanisms.

Journal: Nature communications

Published: June 12, 2024

Design, Synthesis, and Pharmacological Evaluation of Multisubstituted Pyrido[4,3-d]pyrimidine Analogues Bearing Deuterated Methylene Linkers as Potent KRASG12D Inhibitors.

Design, Synthesis, and Pharmacological Evaluation of Multisubstituted Pyrido[4,3-d]pyrimidine Analogues Bearing Deuterated Methylene Linkers as Potent KRASG12D Inhibitors.

Journal: Journal of medicinal chemistry

Published: November 03, 2023

Showing 1-12 of 104

Last Updated: 09/26/2026