April S. Chan

Hong Kong, HCW, Hong Kong Special Administrative Region

Last Updated: 09/26/2026

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Found 9 publications

Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression.

Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression.

Journal: Gut
Published: April 05, 2024

Organoid cultures for cancer modeling.

Organoid cultures for cancer modeling.

Journal: Cell stem cell
Published: November 30, 2022

Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models.

Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models.

Journal: Gut
Published: February 07, 2022

Oncogenic mutations drive intestinal cancer initiation through paracrine remodeling.

Oncogenic mutations drive intestinal cancer initiation through paracrine remodeling.

Journal: Cancer cell
Published: July 14, 2021

Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles.

Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles.

Journal: Gut
Published: October 07, 2019

Breakthrough Moments: Organoid Models of Cancer.

Breakthrough Moments: Organoid Models of Cancer.

Journal: Cell stem cell
Published: June 08, 2019

A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.

A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.

Journal: Cell stem cell
Published: August 17, 2018

MICMIC: identification of DNA methylation of distal regulatory regions with causal effects on tumorigenesis.

MICMIC: identification of DNA methylation of distal regulatory regions with causal effects on tumorigenesis.

Journal: Genome biology
Published: October 27, 2017

Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.

Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.

Journal: Nature genetics
Published: August 01, 2013
Showing 1-9 of 9

Last Updated: 09/26/2026