Last Updated: 09/26/2026
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Found 20 publications
Autonomic Dysfunction Linked to Inhibition of the Nav1.7 Sodium Channel.
Journal: Circulation
Published: April 22, 2024
Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve.
Journal: Channels (Austin, Tex.)
Published: October 14, 2022
An Exploratory Study Using Electronic Medical Records to Assess the Feasibility of Establishing Cohorts of Patients with Genetic Causes of Parkinson's Disease.
Journal: Journal of Parkinson's disease
Published: April 25, 2022
The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease.
Journal: Science translational medicine
Published: January 12, 2022
Translational Pharmacokinetic-Pharmacodynamic Modeling of NaV1.7 Inhibitor MK-2075 to Inform Human Efficacious Dose.
Journal: Frontiers in pharmacology
Published: September 29, 2021
Neurodegenerative Diseases: The Value of Early Predictive End Points.
Journal: Clinical pharmacology and therapeutics
Published: March 22, 2021
A dual-time-window protocol to reduce acquisition time of dynamic tau PET imaging using [18F]MK-6240.
Journal: EJNMMI research
Published: November 23, 2020
Test-retest characteristic of [18F]MK-6240 quantitative outcomes in cognitively normal adults and subjects with Alzheimer's disease.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Published: November 13, 2019
Preclinical Safety Evaluation and Human Dosimetry of [18F]MK-6240, a Novel PET Tracer for Imaging Neurofibrillary Tangles.
Journal: Molecular imaging and biology
Published: May 22, 2019
Brain Imaging of Alzheimer Dementia Patients and Elderly Controls with 18F-MK-6240, a PET Tracer Targeting Neurofibrillary Tangles.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Published: January 12, 2018
A multinational study distinguishing Alzheimer's and healthy patients using cerebrospinal fluid tau/Aβ42 cutoff with concordance to amyloid positron emission tomography imaging.
Journal: Alzheimer's & dementia (Amsterdam, Netherlands)
Published: March 29, 2017
Discovery of 6-(Fluoro-(18)F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs).
Journal: Journal of medicinal chemistry
Published: April 19, 2016
Last Updated: 09/26/2026