Armen O. Simonyan

4 Tikhoretsky Ave
Saint Petersburg, SPE 194064, Russian Federation

Last Updated: 09/26/2026

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Found 14 publications

Molecular Mechanisms of the Deregulation of Muscle Contraction Induced by the R90P Mutation in Tpm3.12 and the Weakening of This Effect by BDM and W7.

Molecular Mechanisms of the Deregulation of Muscle Contraction Induced by the R90P Mutation in Tpm3.12 and the Weakening of This Effect by BDM and W7.

Journal: International journal of molecular sciences

Published: May 12, 2021

Looking for Targets to Restore the Contractile Function in Congenital Myopathy Caused by Gln147Pro Tropomyosin.

Looking for Targets to Restore the Contractile Function in Congenital Myopathy Caused by Gln147Pro Tropomyosin.

Journal: International journal of molecular sciences

Published: August 27, 2020

Combined surgical treatment of a patient with kidney cancer stage 4 and coronary artery disease

Combined surgical treatment of a patient with kidney cancer stage 4 and coronary artery disease

Journal: Khirurgiia

Published: August 02, 2020

Molecular Mechanisms of Muscle Weakness Associated with E173A Mutation in Tpm3.12. Troponin Ca2+ Sensitivity Inhibitor W7 Can Reduce the Damaging Effect of This Mutation.

Molecular Mechanisms of Muscle Weakness Associated with E173A Mutation in Tpm3.12. Troponin Ca2+ Sensitivity Inhibitor W7 Can Reduce the Damaging Effect of This Mutation.

Journal: International journal of molecular sciences

Published: May 30, 2020

The molecular mechanism of muscle dysfunction associated with the R133W mutation in Tpm2.2.

The molecular mechanism of muscle dysfunction associated with the R133W mutation in Tpm2.2.

Journal: Biochemical and biophysical research communications

Published: November 25, 2019

Surgical treatment of pulmonary trunk malignancy

Surgical treatment of pulmonary trunk malignancy

Journal: Khirurgiia

Published: July 30, 2019

The molecular mechanisms of a high Ca2+-sensitivity and muscle weakness associated with the Ala155Thr substitution in Tpm3.12.

The molecular mechanisms of a high Ca2+-sensitivity and muscle weakness associated with the Ala155Thr substitution in Tpm3.12.

Journal: Biochemical and biophysical research communications

Published: May 17, 2019

The Primary Causes of Muscle Dysfunction Associated with the Point Mutations in Tpm3.12; Conformational Analysis of Mutant Proteins as a Tool for Classification of Myopathies.

The Primary Causes of Muscle Dysfunction Associated with the Point Mutations in Tpm3.12; Conformational Analysis of Mutant Proteins as a Tool for Classification of Myopathies.

Journal: International journal of molecular sciences

Published: October 19, 2018

The reason for the low Ca2+-sensitivity of thin filaments associated with the Glu41Lys mutation in the TPM2 gene is "freezing" of tropomyosin near the outer domain of actin and inhibition of actin monomer switching off during the ATPase cycle.

The reason for the low Ca2+-sensitivity of thin filaments associated with the Glu41Lys mutation in the TPM2 gene is "freezing" of tropomyosin near the outer domain of actin and inhibition of actin monomer switching off during the ATPase cycle.

Journal: Biochemical and biophysical research communications

Published: May 14, 2018

The reason for a high Ca2+-sensitivity associated with Arg91Gly substitution in TPM2 gene is the abnormal behavior and high flexibility of tropomyosin during the ATPase cycle.

The reason for a high Ca2+-sensitivity associated with Arg91Gly substitution in TPM2 gene is the abnormal behavior and high flexibility of tropomyosin during the ATPase cycle.

Journal: Biochemical and biophysical research communications

Published: October 25, 2017

The primary cause of muscle disfunction associated with substitutions E240K and R244G in tropomyosin is aberrant behavior of tropomyosin and response of actin and myosin during ATPase cycle.

The primary cause of muscle disfunction associated with substitutions E240K and R244G in tropomyosin is aberrant behavior of tropomyosin and response of actin and myosin during ATPase cycle.

Journal: Archives of biochemistry and biophysics

Published: June 26, 2017

Deviations in conformational rearrangements of thin filaments and myosin caused by the Ala155Thr substitution in hydrophobic core of tropomyosin.

Deviations in conformational rearrangements of thin filaments and myosin caused by the Ala155Thr substitution in hydrophobic core of tropomyosin.

Journal: Biochimica et biophysica acta. Proteins and proteomics

Published: May 04, 2017

Showing 1-12 of 14

Last Updated: 09/26/2026