Armin Sepp

Sheffield, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 25 publications

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement.

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement.

Journal: British journal of clinical pharmacology

Published: November 03, 2025

Correction: Cross-species translational modelling of targeted therapeutic oligonucleotides using physiologically based pharmacokinetics.

Correction: Cross-species translational modelling of targeted therapeutic oligonucleotides using physiologically based pharmacokinetics.

Journal: Journal of pharmacokinetics and pharmacodynamics

Published: July 30, 2025

Understanding antibody-target antigen interactions and the avidity effect using mathematical modelling.

Understanding antibody-target antigen interactions and the avidity effect using mathematical modelling.

Journal: Journal of the Royal Society, Interface

Published: July 08, 2025

Modeling and Simulation Identifies Endocytosis Uptake Rate and Fraction Unbound as Important Predictors of Oligonucleotide Pharmacokinetics.

Modeling and Simulation Identifies Endocytosis Uptake Rate and Fraction Unbound as Important Predictors of Oligonucleotide Pharmacokinetics.

Journal: CPT: pharmacometrics & systems pharmacology

Published: June 23, 2025

The physiological limits of bispecific monoclonal antibody tissue targeting specificity.

The physiological limits of bispecific monoclonal antibody tissue targeting specificity.

Journal: mAbs

Published: April 14, 2025

Accelerating Biologics PBPK Modelling with Automated Model Building: A Tutorial.

Accelerating Biologics PBPK Modelling with Automated Model Building: A Tutorial.

Journal: Pharmaceutics

Published: March 29, 2025

Physiologically Based Pharmacokinetic Modeling of Biologic Case Studies in Monkeys and Humans Reveals the Necessity of an Additional Clearance Term.

Physiologically Based Pharmacokinetic Modeling of Biologic Case Studies in Monkeys and Humans Reveals the Necessity of an Additional Clearance Term.

Journal: Pharmaceutics

Published: March 09, 2025

Cross-species translational modelling of targeted therapeutic oligonucleotides using physiologically based pharmacokinetics.

Cross-species translational modelling of targeted therapeutic oligonucleotides using physiologically based pharmacokinetics.

Journal: Journal of pharmacokinetics and pharmacodynamics

Published: January 29, 2025

The role of automation in enhancing reproducibility and interoperability of PBPK models.

The role of automation in enhancing reproducibility and interoperability of PBPK models.

Journal: Briefings in bioinformatics

Published: January 06, 2025

A Physiologically Based Pharmacokinetic Model Relates the Subcutaneous Bioavailability of Monoclonal Antibodies to the Saturation of FcRn-Mediated Recycling in Injection-Site-Draining Lymph Nodes.

A Physiologically Based Pharmacokinetic Model Relates the Subcutaneous Bioavailability of Monoclonal Antibodies to the Saturation of FcRn-Mediated Recycling in Injection-Site-Draining Lymph Nodes.

Journal: Antibodies (Basel, Switzerland)

Published: July 09, 2024

Application of quantitative protein mass spectrometric data in the early predictive analysis of membrane-bound target engagement by monoclonal antibodies.

Application of quantitative protein mass spectrometric data in the early predictive analysis of membrane-bound target engagement by monoclonal antibodies.

Journal: mAbs

Published: May 03, 2024

Toward systems-informed models for biologics disposition: covariates of the abundance of the neonatal Fc Receptor (FcRn) in human tissues and implications for pharmacokinetic modelling.

Toward systems-informed models for biologics disposition: covariates of the abundance of the neonatal Fc Receptor (FcRn) in human tissues and implications for pharmacokinetic modelling.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: October 15, 2022

Showing 1-12 of 25

Last Updated: 09/26/2026