Aroli Marcellinus

Gumi, Republic of Korea

Last Updated: 09/26/2026

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Found 18 publications

Incorporating inter-individual variability to improve the reliability of predicted outcomes in in silico cardiac safety assessment.

Incorporating inter-individual variability to improve the reliability of predicted outcomes in in silico cardiac safety assessment.

Journal: Toxicology and applied pharmacology

Published: March 02, 2026

Improving In Silico Cardiac Safety Prediction by Consensus Averaging of Transmural Ventricular Cell Models.

Improving In Silico Cardiac Safety Prediction by Consensus Averaging of Transmural Ventricular Cell Models.

Journal: Annals of biomedical engineering

Published: September 09, 2025

In silico cardiac safety assessment using a multi-biomarker approach based on an electrophysiological model of hiPSC-derived cardiomyocytes.

In silico cardiac safety assessment using a multi-biomarker approach based on an electrophysiological model of hiPSC-derived cardiomyocytes.

Journal: Toxicological research

Published: August 06, 2025

A multiscale computational model of cardiac electrophysiology for drug-induced pro-arrhythmic risk stratification.

A multiscale computational model of cardiac electrophysiology for drug-induced pro-arrhythmic risk stratification.

Journal: Biomedical engineering letters

Published: April 06, 2025

Cardiotoxicity evaluation of two-drug fixed-dose combination therapy under CiPA: a computational study.

Cardiotoxicity evaluation of two-drug fixed-dose combination therapy under CiPA: a computational study.

Journal: Translational and clinical pharmacology

Published: September 30, 2024

A stacking ensemble machine learning model for evaluating cardiac toxicity of drugs based on in silico biomarkers.

A stacking ensemble machine learning model for evaluating cardiac toxicity of drugs based on in silico biomarkers.

Journal: CPT: pharmacometrics & systems pharmacology

Published: April 23, 2024

Development of in-silico drug cardiac toxicity evaluation system with consideration of inter-individual variability.

Development of in-silico drug cardiac toxicity evaluation system with consideration of inter-individual variability.

Journal: Translational and clinical pharmacology

Published: March 03, 2024

Evaluation of cardiac pro-arrhythmic risks using the artificial neural network with ToR-ORd in silico model output.

Evaluation of cardiac pro-arrhythmic risks using the artificial neural network with ToR-ORd in silico model output.

Journal: Frontiers in physiology

Published: January 22, 2024

qInward variability-based in-silico proarrhythmic risk assessment of drugs using deep learning model.

qInward variability-based in-silico proarrhythmic risk assessment of drugs using deep learning model.

Journal: Frontiers in physiology

Published: October 26, 2022

Application of Convolutional Neural Networks Using Action Potential Shape for In-Silico Proarrhythmic Risk Assessment.

Application of Convolutional Neural Networks Using Action Potential Shape for In-Silico Proarrhythmic Risk Assessment.

Journal: Biomedicines

Published: September 29, 2022

Verification of the Efficacy of Mexiletine Treatment for the A1656D Mutation on Downgrading Reentrant Tachycardia Using a 3D Cardiac Electrophysiological Model.

Verification of the Efficacy of Mexiletine Treatment for the A1656D Mutation on Downgrading Reentrant Tachycardia Using a 3D Cardiac Electrophysiological Model.

Journal: Bioengineering (Basel, Switzerland)

Published: September 15, 2022

Sensitivity Analysis of Cardiac Alternans and Tachyarrhythmia to Ion Channel Conductance Using Population Modeling.

Sensitivity Analysis of Cardiac Alternans and Tachyarrhythmia to Ion Channel Conductance Using Population Modeling.

Journal: Bioengineering (Basel, Switzerland)

Published: August 29, 2022

Showing 1-12 of 18

Last Updated: 09/26/2026