Arthur Van Aerschot

Leuven, VLG, Belgium

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 40 publications

Crystal structure of Mycobacterium tuberculosis mycothione reductase in complex with a specific inhibitor reveals competition with NADP(H) binding.

Crystal structure of Mycobacterium tuberculosis mycothione reductase in complex with a specific inhibitor reveals competition with NADP(H) binding.

Journal: FEBS letters

Published: December 16, 2025

Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.

Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.

Journal: European journal of medicinal chemistry

Published: July 29, 2024

Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides.

Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides.

Journal: International journal of molecular sciences

Published: November 11, 2022

Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip.

Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip.

Journal: Communications biology

Published: March 07, 2022

Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors.

Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors.

Journal: RSC chemical biology

Published: February 18, 2022

Towards Novel 3-Aminopyrazinamide-Based Prolyl-tRNA Synthetase Inhibitors: In Silico Modelling, Thermal Shift Assay and Structural Studies.

Towards Novel 3-Aminopyrazinamide-Based Prolyl-tRNA Synthetase Inhibitors: In Silico Modelling, Thermal Shift Assay and Structural Studies.

Journal: International journal of molecular sciences

Published: May 25, 2021

Aminoacyl-tRNA Synthetases as Valuable Targets for Antimicrobial Drug Discovery.

Aminoacyl-tRNA Synthetases as Valuable Targets for Antimicrobial Drug Discovery.

Journal: International journal of molecular sciences

Published: January 18, 2021

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors.

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors.

Journal: Molecules (Basel, Switzerland)

Published: September 24, 2020

Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors.

Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors.

Journal: European journal of medicinal chemistry

Published: August 11, 2020

Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase.

Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase.

Journal: Bioorganic & medicinal chemistry

Published: June 02, 2020

Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase.

Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase.

Journal: Bioorganic & medicinal chemistry

Published: March 18, 2020

Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.

Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.

Journal: ACS chemical biology

Published: December 24, 2019

Showing 1-12 of 40

Last Updated: 09/26/2026