Atsuo Tanimoto
Takatsuki, Japan
Last Updated: 09/26/2026
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Found 9 publications
SAR study of small molecule inhibitors of the programmed cell death-1/programmed cell death-ligand 1 interaction.
Journal: Chemical biology & drug design
Published: February 14, 2021
Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders.
Journal: Journal of medicinal chemistry
Published: June 09, 2020
Symmetry-based ligand design and evaluation of small molecule inhibitors of programmed cell death-1/programmed death-ligand 1 interaction.
Journal: Bioorganic & medicinal chemistry letters
Published: June 12, 2019
Janus kinase inhibitor delgocitinib suppresses pruritus and nerve elongation in an atopic dermatitis murine model.
Journal: Journal of dermatological science
Published: April 26, 2019
A novel JAK inhibitor JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents.
Journal: Experimental dermatology
Published: April 13, 2017
JAK inhibitor JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation.
Journal: Journal of dermatological science
Published: April 11, 2016
Improvement of spontaneous locomotor activity with JAK inhibition by JTE-052 in rat adjuvant-induced arthritis.
Journal: BMC musculoskeletal disorders
Published: March 05, 2015
The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling.
Journal: The Journal of allergy and clinical immunology
Published: November 06, 2014
Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Published: February 07, 2014
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Last Updated: 09/26/2026