Attila Lehotzky

Budapest, BU 1117, Hungary

Last Updated: 09/26/2026

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Found 21 publications

Perspective Strategies for Interventions in Parkinsonism: Remedying the Neglected Role of TPPP.

Perspective Strategies for Interventions in Parkinsonism: Remedying the Neglected Role of TPPP.

Journal: Cells

Published: December 26, 2023

Modulatory Role of TPPP3 in Microtubule Organization and Its Impact on Alpha-Synuclein Pathology.

Modulatory Role of TPPP3 in Microtubule Organization and Its Impact on Alpha-Synuclein Pathology.

Journal: Cells

Published: September 13, 2022

Challenges in Discovering Drugs That Target the Protein-Protein Interactions of Disordered Proteins.

Challenges in Discovering Drugs That Target the Protein-Protein Interactions of Disordered Proteins.

Journal: International journal of molecular sciences

Published: January 17, 2022

Anti-Aggregative Effect of the Antioxidant DJ-1 on the TPPP/p25-Derived Pathological Associations of Alpha-Synuclein.

Anti-Aggregative Effect of the Antioxidant DJ-1 on the TPPP/p25-Derived Pathological Associations of Alpha-Synuclein.

Journal: Cells

Published: September 10, 2021

Co-Transmission of Alpha-Synuclein and TPPP/p25 Inhibits Their Proteolytic Degradation in Human Cell Models.

Co-Transmission of Alpha-Synuclein and TPPP/p25 Inhibits Their Proteolytic Degradation in Human Cell Models.

Journal: Frontiers in molecular biosciences

Published: February 09, 2021

HaloTag-Targeted Sirtuin-Rearranging Ligand (SirReal) for the Development of Proteolysis-Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2)*.

HaloTag-Targeted Sirtuin-Rearranging Ligand (SirReal) for the Development of Proteolysis-Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2)*.

Journal: Chembiochem : a European journal of chemical biology

Published: June 04, 2020

Microtubule-Associated Proteins with Regulatory Functions by Day and Pathological Potency at Night.

Microtubule-Associated Proteins with Regulatory Functions by Day and Pathological Potency at Night.

Journal: Cells

Published: December 13, 2019

Interactions between two regulatory proteins of microtubule dynamics, HDAC6, TPPP/p25, and the hub protein, DYNLL/LC8.

Interactions between two regulatory proteins of microtubule dynamics, HDAC6, TPPP/p25, and the hub protein, DYNLL/LC8.

Journal: Biochimica et biophysica acta. Molecular cell research

Published: May 07, 2019

New chemical tools for probing activity and inhibition of the NAD+-dependent lysine deacylase sirtuin 2.

New chemical tools for probing activity and inhibition of the NAD+-dependent lysine deacylase sirtuin 2.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Published: September 06, 2017

Modulation Of Microtubule Acetylation By The Interplay Of TPPP/p25, SIRT2 And New Anticancer Agents With Anti-SIRT2 Potency.

Modulation Of Microtubule Acetylation By The Interplay Of TPPP/p25, SIRT2 And New Anticancer Agents With Anti-SIRT2 Potency.

Journal: Scientific reports

Published: May 15, 2017

Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals).

Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals).

Journal: Journal of medicinal chemistry

Published: April 06, 2017

Challenging drug target for Parkinson's disease: Pathological complex of the chameleon TPPP/p25 and alpha-synuclein proteins.

Challenging drug target for Parkinson's disease: Pathological complex of the chameleon TPPP/p25 and alpha-synuclein proteins.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: June 30, 2016

Showing 1-12 of 21

Last Updated: 09/26/2026