Axel Pahler

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 33 publications

Meeting report of the 6th European Biotransformation Workshop.

Meeting report of the 6th European Biotransformation Workshop.

Journal: Xenobiotica; the fate of foreign compounds in biological systems

Published: May 11, 2026

High-Throughput Physiologically Based Pharmacokinetic Model for Rodent Pharmacokinetics Prediction Using Machine Learning-Predicted Inputs and a Large In Vivo Pharmacokinetics Data Set.

High-Throughput Physiologically Based Pharmacokinetic Model for Rodent Pharmacokinetics Prediction Using Machine Learning-Predicted Inputs and a Large In Vivo Pharmacokinetics Data Set.

Journal: Molecular pharmaceutics

Published: January 30, 2026

Novel selective morpholine trace amine-associated receptor 1 partial agonists show promising preclinical effects for neuropsychiatric disorders and are well tolerated in healthy volunteers.

Novel selective morpholine trace amine-associated receptor 1 partial agonists show promising preclinical effects for neuropsychiatric disorders and are well tolerated in healthy volunteers.

Journal: Molecular psychiatry

Published: July 23, 2025

Preclinical development of [18F]TAAR1-2203 as a PET radioligand for imaging TAAR1 expression and receptor occupancy.

Preclinical development of [18F]TAAR1-2203 as a PET radioligand for imaging TAAR1 expression and receptor occupancy.

Journal: European journal of nuclear medicine and molecular imaging

Published: July 07, 2025

The "five-star matrix" for patient-centric drug discovery and development in neuroscience.

The "five-star matrix" for patient-centric drug discovery and development in neuroscience.

Journal: Neuron

Published: February 02, 2025

Novel Macrocyclic NLRP3 Inhibitors.

Novel Macrocyclic NLRP3 Inhibitors.

Journal: Journal of medicinal chemistry

Published: November 25, 2024

Meeting report of the 5th European Biotransformation Workshop.

Meeting report of the 5th European Biotransformation Workshop.

Journal: Xenobiotica; the fate of foreign compounds in biological systems

Published: September 03, 2024

Meeting report of the 4th European biotransformation workshop.

Meeting report of the 4th European biotransformation workshop.

Journal: Xenobiotica; the fate of foreign compounds in biological systems

Published: January 05, 2024

Evaluation of the drug disposition of RO7049389 with in vitro data and human mass balance supported by physiologically based pharmacokinetic modelling.

Evaluation of the drug disposition of RO7049389 with in vitro data and human mass balance supported by physiologically based pharmacokinetic modelling.

Journal: British journal of clinical pharmacology

Published: April 05, 2023

Meeting report of the 3rd European Biotransformation Workshop.

Meeting report of the 3rd European Biotransformation Workshop.

Journal: Xenobiotica; the fate of foreign compounds in biological systems

Published: January 24, 2023

RO6807936 as a novel positron emission tomography (PET) radiotracer for in vitro and in vivo visualization and quantification of beta-site amyloid precursor protein cleaving enzyme (BACE1) in the rodent and baboon brain.

RO6807936 as a novel positron emission tomography (PET) radiotracer for in vitro and in vivo visualization and quantification of beta-site amyloid precursor protein cleaving enzyme (BACE1) in the rodent and baboon brain.

Journal: Journal of labelled compounds & radiopharmaceuticals

Published: December 21, 2022

Meeting report of the second European biotransformation workshop.

Meeting report of the second European biotransformation workshop.

Journal: Xenobiotica; the fate of foreign compounds in biological systems

Published: April 12, 2022

Showing 1-12 of 33

Last Updated: 09/26/2026