Baolian O. Wang

Beijing Key Laboratory Of Active Substances Discovery And Druggability Evaluation, Chinese Academy Of Medical Sciences And Peking Union Medical College
Beijing, 100050, China

Last Updated: 09/26/2026

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Found 50 publications

Discovery of 1H-Indole-3-Propionamide Derivatives as Potent, Selective and Orally Available NaV1.7 Inhibitors for Pain Treatment.

Discovery of 1H-Indole-3-Propionamide Derivatives as Potent, Selective and Orally Available NaV1.7 Inhibitors for Pain Treatment.

Journal: Journal of medicinal chemistry

Published: July 27, 2026

Discovery and Optimization of 4-Methylquinazoline Derivatives as Highly Selective PI3Kδ Inhibitors for the Treatment of Acute Lung Injury.

Discovery and Optimization of 4-Methylquinazoline Derivatives as Highly Selective PI3Kδ Inhibitors for the Treatment of Acute Lung Injury.

Journal: Journal of medicinal chemistry

Published: May 24, 2026

Discovery of Potent Benzoselenazinone-Based DprE1 Inhibitors: A Novel Selenium-Containing Scaffold with Superior Anti-TB Activity and Pharmacokinetic Properties.

Discovery of Potent Benzoselenazinone-Based DprE1 Inhibitors: A Novel Selenium-Containing Scaffold with Superior Anti-TB Activity and Pharmacokinetic Properties.

Journal: Journal of medicinal chemistry

Published: April 17, 2026

Structure-enabled discovery of carboxylate esters prodrugs as potential potent inhibitors targeting Glutaminase C.

Structure-enabled discovery of carboxylate esters prodrugs as potential potent inhibitors targeting Glutaminase C.

Journal: Bioorganic chemistry

Published: September 28, 2025

One-Shot Rational Design of Covalent Drugs with CovalentLab.

One-Shot Rational Design of Covalent Drugs with CovalentLab.

Journal: JACS Au

Published: September 05, 2025

Deep learning-based discovery of tetrahydrocarbazoles as broad-spectrum antitumor agents and click-activated strategy for targeted cancer therapy.

Deep learning-based discovery of tetrahydrocarbazoles as broad-spectrum antitumor agents and click-activated strategy for targeted cancer therapy.

Journal: Acta pharmaceutica Sinica. B

Published: March 04, 2025

Saorilao Qingfei Zhike Capsule alleviated inflammation and bronchial remodeling in LPS and CS-induced COPD via MAPK signaling pathway.

Saorilao Qingfei Zhike Capsule alleviated inflammation and bronchial remodeling in LPS and CS-induced COPD via MAPK signaling pathway.

Journal: Journal of ethnopharmacology

Published: March 02, 2025

Absorption, distribution, metabolism, and excretion (ADME) of R,S-Goitrin in Radix Isatidis in rats by LC-MS/MS determination.

Absorption, distribution, metabolism, and excretion (ADME) of R,S-Goitrin in Radix Isatidis in rats by LC-MS/MS determination.

Journal: Fitoterapia

Published: January 06, 2025

Pharmacokinetics and related gender difference studies of four active components of Codonopsis Pilosula by LC-MS/MS determination.

Pharmacokinetics and related gender difference studies of four active components of Codonopsis Pilosula by LC-MS/MS determination.

Journal: Journal of ethnopharmacology

Published: July 15, 2024

Bioequivalence Analysis of Terazosin Hydrochloride Tablets Based on Parallel Artificial Membrane Permeability Analysis.

Bioequivalence Analysis of Terazosin Hydrochloride Tablets Based on Parallel Artificial Membrane Permeability Analysis.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: June 15, 2024

Design, Synthesis, and Biological Evaluation of 1,2,4-Oxadiazole Derivatives Containing an Aryl Carboxylic Acid Moiety as Potent Sarbecovirus Papain-like Protease Inhibitors.

Design, Synthesis, and Biological Evaluation of 1,2,4-Oxadiazole Derivatives Containing an Aryl Carboxylic Acid Moiety as Potent Sarbecovirus Papain-like Protease Inhibitors.

Journal: Journal of medicinal chemistry

Published: June 13, 2024

Identification of a novel xanthine oxidoreductase inhibitor for hyperuricemia treatment with high efficacy and safety profile.

Identification of a novel xanthine oxidoreductase inhibitor for hyperuricemia treatment with high efficacy and safety profile.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: May 23, 2024

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Last Updated: 09/26/2026