Barbara A. Dymek

Warsaw, MZ, Poland

Last Updated: 09/26/2026

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Found 15 publications

Chitinase-1 inhibition attenuates metabolic dysregulation and restores homeostasis in MASH animal models.

Chitinase-1 inhibition attenuates metabolic dysregulation and restores homeostasis in MASH animal models.

Journal: Frontiers in immunology

Published: December 13, 2024

Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma.

Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma.

Journal: International journal of molecular sciences

Published: January 23, 2023

The Role of Chitinases in Chronic Airway Inflammation Associated with Tobacco Smoke Exposure.

The Role of Chitinases in Chronic Airway Inflammation Associated with Tobacco Smoke Exposure.

Journal: Cells

Published: September 19, 2022

Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis.

Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis.

Journal: Journal of inflammation research

Published: July 13, 2022

Design, Synthesis, and Development of pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part I-Indole Derivatives.

Design, Synthesis, and Development of pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part I-Indole Derivatives.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: June 22, 2022

Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis.

Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis.

Journal: European journal of pharmacology

Published: September 02, 2021

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.

Journal: Journal of medicinal chemistry

Published: October 20, 2020

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase.

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase.

Journal: ACS medicinal chemistry letters

Published: February 21, 2020

Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors.

Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors.

Journal: ACS medicinal chemistry letters

Published: November 05, 2019

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases.

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases.

Journal: Journal of medicinal chemistry

Published: July 11, 2019

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.

Journal: Journal of medicinal chemistry

Published: December 29, 2017

Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase.

Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase.

Journal: Bioorganic & medicinal chemistry letters

Published: September 16, 2017

Showing 1-12 of 15

Last Updated: 09/26/2026