Barbara Mair

160 College Street
Toronto, ON, Canada

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 23 publications

Quantitative analysis of genetic interactions in human cells from genome-wide CRISPR-Cas9 screens.

Quantitative analysis of genetic interactions in human cells from genome-wide CRISPR-Cas9 screens.

Journal: bioRxiv : the preprint server for biology
Published: January 16, 2026

Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles.

Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles.

Journal: Cell
Published: November 25, 2025

A global genetic interaction map of a human cell reveals conserved principles of genetic networks.

A global genetic interaction map of a human cell reveals conserved principles of genetic networks.

Journal: bioRxiv : the preprint server for biology
Published: July 09, 2025

SOS1 inhibitor BI-3406 shows in vivo antitumor activity akin to genetic ablation and synergizes with a KRASG12D inhibitor in KRAS LUAD.

SOS1 inhibitor BI-3406 shows in vivo antitumor activity akin to genetic ablation and synergizes with a KRASG12D inhibitor in KRAS LUAD.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 12, 2025

SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma.

SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma.

Journal: bioRxiv : the preprint server for biology
Published: December 18, 2023

Genetic dependencies associated with transcription factor activities in human cancer cell lines.

Genetic dependencies associated with transcription factor activities in human cancer cell lines.

Journal: Cell reports
Published: March 14, 2023

A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo.

A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo.

Journal: Nature communications
Published: March 02, 2022

A cohesin traffic pattern genetically linked to gene regulation.

A cohesin traffic pattern genetically linked to gene regulation.

Journal: Nature structural & molecular biology
Published: December 13, 2021

A Method to Map Gene Essentiality of Human Pluripotent Stem Cells by Genome-Scale CRISPR Screens with Inducible Cas9.

A Method to Map Gene Essentiality of Human Pluripotent Stem Cells by Genome-Scale CRISPR Screens with Inducible Cas9.

Journal: Methods in molecular biology (Clifton, N.J.)
Published: October 28, 2021

Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes.

Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes.

Journal: Cell reports
Published: May 27, 2021

Digital microfluidic isolation of single cells for -Omics.

Digital microfluidic isolation of single cells for -Omics.

Journal: Nature communications
Published: June 09, 2020

CRISPR screens are feasible in TP53 wild-type cells.

CRISPR screens are feasible in TP53 wild-type cells.

Journal: Molecular systems biology
Published: August 30, 2019
Showing 1-12 of 23

Last Updated: 09/26/2026