Beat Ernst

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 72 publications

Design, synthesis and biophysical evaluation of sialyl triazoles as glycomimetic ligands for Siglec-8. Sulfonate is a viable replacement for sulfate.

Design, synthesis and biophysical evaluation of sialyl triazoles as glycomimetic ligands for Siglec-8. Sulfonate is a viable replacement for sulfate.

Journal: European journal of medicinal chemistry

Published: January 20, 2026

Acid Versus Amide-Facts and Fallacies: A Case Study in Glycomimetic Ligand Design.

Acid Versus Amide-Facts and Fallacies: A Case Study in Glycomimetic Ligand Design.

Journal: Molecules (Basel, Switzerland)

Published: October 27, 2025

Thermodynamics-Guided Design Reveals a Cooperative Hydrogen Bond in DC-SIGN-targeted Glycomimetics.

Thermodynamics-Guided Design Reveals a Cooperative Hydrogen Bond in DC-SIGN-targeted Glycomimetics.

Journal: Journal of medicinal chemistry

Published: May 21, 2024

Strengthening an Intramolecular Non-Classical Hydrogen Bond to Get in Shape for Binding.

Strengthening an Intramolecular Non-Classical Hydrogen Bond to Get in Shape for Binding.

Journal: Angewandte Chemie (International ed. in English)

Published: April 03, 2024

Analogues of the pan-selectin antagonist rivipansel (GMI-1070).

Analogues of the pan-selectin antagonist rivipansel (GMI-1070).

Journal: European journal of medicinal chemistry

Published: March 09, 2024

Tetra- and Hexavalent Siglec-8 Ligands Modulate Immune Cell Activation.

Tetra- and Hexavalent Siglec-8 Ligands Modulate Immune Cell Activation.

Journal: Angewandte Chemie (International ed. in English)

Published: September 26, 2023

Does size matter? - Comparing pyranoses with septanoses as ligands of the bacterial lectin FimH.

Does size matter? - Comparing pyranoses with septanoses as ligands of the bacterial lectin FimH.

Journal: European journal of medicinal chemistry

Published: September 09, 2023

Combating DC-SIGN-mediated SARS-CoV-2 dissemination by glycan-mimicking polymers.

Combating DC-SIGN-mediated SARS-CoV-2 dissemination by glycan-mimicking polymers.

Journal: Archiv der Pharmazie

Published: July 20, 2023

Nature of the Interaction of Alpha-D-Mannose and Escherichia coli Bacteria, and Implications for its Regulatory Classification. A Delphi Panel European Consensus Based on Chemistry and Legal Evidence.

Nature of the Interaction of Alpha-D-Mannose and Escherichia coli Bacteria, and Implications for its Regulatory Classification. A Delphi Panel European Consensus Based on Chemistry and Legal Evidence.

Journal: Therapeutic innovation & regulatory science

Published: March 15, 2023

Glycopolymer binds pathogenic IgM autoantibodies and pulls them into the mononuclear phagocyte system for degradation.

Glycopolymer binds pathogenic IgM autoantibodies and pulls them into the mononuclear phagocyte system for degradation.

Journal: Scientific reports

Published: February 19, 2023

A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewisx Mimetics.

A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewisx Mimetics.

Journal: Molecules (Basel, Switzerland)

Published: January 15, 2023

Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth.

Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth.

Journal: ACS chemical biology

Published: June 08, 2022

Showing 1-12 of 72

Last Updated: 09/26/2026