Benedicte F. Py

Lyon, 69007, France

Last Updated: 09/26/2026

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Found 40 publications

Statins promote muscle metabolic danger and NLRP3-mediated myopathy via lower protein-prenylation and YAP.

Statins promote muscle metabolic danger and NLRP3-mediated myopathy via lower protein-prenylation and YAP.

Journal: Science advances

Published: June 19, 2026

CRY-NLRP3 complexes define a circadian checkpoint controlling inflammasome activation.

CRY-NLRP3 complexes define a circadian checkpoint controlling inflammasome activation.

Journal: bioRxiv : the preprint server for biology

Published: May 13, 2026

Pharmacological targeting of the NLRP3 LRR domain with isothiazolinones overcomes CRID3-resistant inflammation.

Pharmacological targeting of the NLRP3 LRR domain with isothiazolinones overcomes CRID3-resistant inflammation.

Journal: EMBO molecular medicine

Published: November 06, 2025

Circulating cochlin LCCL domain binds to dying cells and enhances efferocytosis.

Circulating cochlin LCCL domain binds to dying cells and enhances efferocytosis.

Journal: Cell reports

Published: October 07, 2025

IRF2 deficiency disrupts pyroptosis, NK cell interferon-γ production and resistance to Francisella.

IRF2 deficiency disrupts pyroptosis, NK cell interferon-γ production and resistance to Francisella.

Journal: EMBO reports

Published: February 25, 2025

Functional analysis of NLRP3 variants provides insight into inflammasome regulation.

Functional analysis of NLRP3 variants provides insight into inflammasome regulation.

Journal: Nature immunology

Published: February 20, 2025

A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation.

A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation.

Journal: Cell chemical biology

Published: February 07, 2025

Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action.

Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action.

Journal: The Journal of experimental medicine

Published: December 17, 2024

Functional diversity of NLRP3 gain-of-function mutations and impact on the diagnosis of CAPS hereditary auto-inflammation disease

Functional diversity of NLRP3 gain-of-function mutations and impact on the diagnosis of CAPS hereditary auto-inflammation disease

Journal: Medecine sciences : M/S

Published: October 25, 2024

Implication of the LRR Domain in the Regulation and Activation of the NLRP3 Inflammasome.

Implication of the LRR Domain in the Regulation and Activation of the NLRP3 Inflammasome.

Journal: Cells

Published: July 09, 2024

Optogenetically controlled inflammasome activation demonstrates two phases of cell swelling during pyroptosis.

Optogenetically controlled inflammasome activation demonstrates two phases of cell swelling during pyroptosis.

Journal: Science signaling

Published: April 23, 2024

Altered Ex Vivo NLRP3 Inflammasome Activation Is Associated with 28-Day Mortality in Septic Patients.

Altered Ex Vivo NLRP3 Inflammasome Activation Is Associated with 28-Day Mortality in Septic Patients.

Journal: Viruses

Published: November 06, 2023

Showing 1-12 of 40

Last Updated: 09/26/2026