Benjamin Boucherle

Grenoble, 38000, France

Last Updated: 09/26/2026

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Found 20 publications

Contrasting Impacts of Two ABCB11 Variants Affecting the Same Residue in Progressive Familial Intrahepatic Cholestasis Type 2.

Contrasting Impacts of Two ABCB11 Variants Affecting the Same Residue in Progressive Familial Intrahepatic Cholestasis Type 2.

Journal: American journal of physiology. Gastrointestinal and liver physiology

Published: August 05, 2026

ABCB4 disease-causing variants S242R, S346I, T437I and T1077M significantly impair its function and display differential sensitivity to potentiators.

ABCB4 disease-causing variants S242R, S346I, T437I and T1077M significantly impair its function and display differential sensitivity to potentiators.

Journal: Scientific reports

Published: May 13, 2025

Expanding Chemical Frontiers: Approaches for Generating Diverse and Bioactive Natural Product-Like Compounds Libraries from Extracts.

Expanding Chemical Frontiers: Approaches for Generating Diverse and Bioactive Natural Product-Like Compounds Libraries from Extracts.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: December 14, 2023

Aurones and derivatives as promising New Delhi metallo-β-lactamase (NDM-1) inhibitors.

Aurones and derivatives as promising New Delhi metallo-β-lactamase (NDM-1) inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: July 10, 2023

Investigation of Chemical Composition and Biological Activities of Ajuga pyramidalis-Isolation of Iridoids and Phenylethanoid Glycosides.

Investigation of Chemical Composition and Biological Activities of Ajuga pyramidalis-Isolation of Iridoids and Phenylethanoid Glycosides.

Journal: Metabolites

Published: December 22, 2022

A fragment-based drug discovery strategy applied to the identification of NDM-1 β-lactamase inhibitors.

A fragment-based drug discovery strategy applied to the identification of NDM-1 β-lactamase inhibitors.

Journal: European journal of medicinal chemistry

Published: April 23, 2022

Exploring the structure-activity relationship of benzylidene-2,3-dihydro-1H-inden-1-one compared to benzofuran-3(2H)-one derivatives as inhibitors of tau amyloid fibers.

Exploring the structure-activity relationship of benzylidene-2,3-dihydro-1H-inden-1-one compared to benzofuran-3(2H)-one derivatives as inhibitors of tau amyloid fibers.

Journal: European journal of medicinal chemistry

Published: September 26, 2021

β-Carboline as a Privileged Scaffold for Multitarget Strategies in Alzheimer's Disease Therapy.

β-Carboline as a Privileged Scaffold for Multitarget Strategies in Alzheimer's Disease Therapy.

Journal: Journal of medicinal chemistry

Published: February 02, 2021

Development of an innovative maceration technique to optimize extraction and phase partition of natural products.

Development of an innovative maceration technique to optimize extraction and phase partition of natural products.

Journal: Fitoterapia

Published: November 05, 2020

Phytochemical and Biological Investigation of Helianthemum nummularium, a High-Altitude Growing Alpine Plant Overrepresented in Ungulates Diets.

Phytochemical and Biological Investigation of Helianthemum nummularium, a High-Altitude Growing Alpine Plant Overrepresented in Ungulates Diets.

Journal: Planta medica

Published: July 10, 2020

Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity.

Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity.

Journal: European journal of medicinal chemistry

Published: August 16, 2019

Could we expect new praziquantel derivatives? A meta pharmacometrics/pharmacoinformatics analysis of all antischistosomal praziquantel derivatives found in the literature.

Could we expect new praziquantel derivatives? A meta pharmacometrics/pharmacoinformatics analysis of all antischistosomal praziquantel derivatives found in the literature.

Journal: SAR and QSAR in environmental research

Published: May 31, 2019

Showing 1-12 of 20

Last Updated: 09/26/2026