Bernard Fromenty

Rennes, 35000, France

Last Updated: 09/26/2026

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Found 65 publications

The history of β-aminoisobutyric acid: from a waste metabolite to a druggable compound for metabolic disease. A narrative review.

The history of β-aminoisobutyric acid: from a waste metabolite to a druggable compound for metabolic disease. A narrative review.

Journal: European journal of pharmacology

Published: November 18, 2025

The dithiocarbamate pesticides maneb and mancozeb disturb the metabolism of lipids and xenobiotics in an in vitro model of metabolic dysfunction-associated steatotic liver disease.

The dithiocarbamate pesticides maneb and mancozeb disturb the metabolism of lipids and xenobiotics in an in vitro model of metabolic dysfunction-associated steatotic liver disease.

Journal: Environmental toxicology and pharmacology

Published: March 27, 2025

PPARγ, a key modulator of metabolic reprogramming, stemness and chemoresistance associated with retrodifferentiation in human hepatocellular carcinomas.

PPARγ, a key modulator of metabolic reprogramming, stemness and chemoresistance associated with retrodifferentiation in human hepatocellular carcinomas.

Journal: Cell death & disease

Published: December 09, 2024

Mitochondrial dysfunction in drug-induced hepatic steatosis: Recent findings and current concept.

Mitochondrial dysfunction in drug-induced hepatic steatosis: Recent findings and current concept.

Journal: Clinics and research in hepatology and gastroenterology

Published: October 01, 2024

Drug-induced impairment of mitochondrial fatty acid oxidation and steatosis: assessment of causal relationship with 45 pharmaceuticals.

Drug-induced impairment of mitochondrial fatty acid oxidation and steatosis: assessment of causal relationship with 45 pharmaceuticals.

Journal: Toxicological sciences : an official journal of the Society of Toxicology

Published: April 27, 2024

Weight of evidence evaluation of the metabolism disrupting effects of triphenyl phosphate using an expert knowledge elicitation approach.

Weight of evidence evaluation of the metabolism disrupting effects of triphenyl phosphate using an expert knowledge elicitation approach.

Journal: Toxicology and applied pharmacology

Published: March 18, 2024

Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet.

Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet.

Journal: Pharmacological research

Published: November 07, 2023

A strategy to detect metabolic changes induced by exposure to chemicals from large sets of condition-specific metabolic models computed with enumeration techniques.

A strategy to detect metabolic changes induced by exposure to chemicals from large sets of condition-specific metabolic models computed with enumeration techniques.

Journal: BMC bioinformatics

Published: September 28, 2023

Low concentrations of ethylene bisdithiocarbamate pesticides maneb and mancozeb impair manganese and zinc homeostasis to induce oxidative stress and caspase-dependent apoptosis in human hepatocytes.

Low concentrations of ethylene bisdithiocarbamate pesticides maneb and mancozeb impair manganese and zinc homeostasis to induce oxidative stress and caspase-dependent apoptosis in human hepatocytes.

Journal: Chemosphere

Published: May 02, 2023

Mitochondrial remodeling and energy metabolism adaptations in colonic crypts during spontaneous epithelial repair after colitis induction in mice.

Mitochondrial remodeling and energy metabolism adaptations in colonic crypts during spontaneous epithelial repair after colitis induction in mice.

Journal: Free radical biology & medicine

Published: April 17, 2023

3D multi-cell-type liver organoids: A new model of non-alcoholic fatty liver disease for drug safety assessments.

3D multi-cell-type liver organoids: A new model of non-alcoholic fatty liver disease for drug safety assessments.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: March 10, 2023

Acetaminophen-Induced Hepatotoxicity in Obesity and Nonalcoholic Fatty Liver Disease: A Critical Review.

Acetaminophen-Induced Hepatotoxicity in Obesity and Nonalcoholic Fatty Liver Disease: A Critical Review.

Journal: Livers

Published: January 30, 2023

Showing 1-12 of 65

Last Updated: 09/26/2026