Bernard Refouvelet
Besancon, 25000, France
Last Updated: 09/26/2026
Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 19 publications
Multicomponent Synthesis of Multi-Target Quinazolines Modulating Cholinesterase, Oxidative Stress, and Amyloid Aggregation Activities for the Therapy of Alzheimer's Disease.
Journal: Molecules (Basel, Switzerland)
Published: September 01, 2025
Discovery of New Highly Potent Histamine H3 Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors.
Journal: ACS chemical neuroscience
Published: August 29, 2024
Synthesis and evaluation of lipoic acid - donepezil hybrids for Alzheimer's disease using a straightforward strategy.
Journal: Bioorganic & medicinal chemistry letters
Published: June 13, 2024
Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer's Disease Treatment.
Journal: International journal of molecular sciences
Published: April 03, 2023
Multicomponent reactions as a privileged tool for multitarget-directed ligand strategies in Alzheimer's disease therapy.
Journal: Future medicinal chemistry
Published: October 20, 2022
Latest progress in the development of multitarget ligands for Alzheimer's disease based on the Hantzsch reaction.
Journal: Future medicinal chemistry
Published: May 24, 2022
(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease.
Journal: ACS chemical neuroscience
Published: April 02, 2021
Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives.
Journal: International journal of molecular sciences
Published: September 11, 2020
Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy.
Journal: International journal of molecular sciences
Published: April 10, 2020
Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels.
Journal: Molecules (Basel, Switzerland)
Published: February 28, 2020
Synthesis of new ferulic/lipoic/comenic acid-melatonin hybrids as antioxidants and Nrf2 activators via Ugi reaction.
Journal: Future medicinal chemistry
Published: December 17, 2019
Synthesis and Biological Evaluation of Novel Chromone+Donepezil Hybrids for Alzheimer's Disease Therapy.
Journal: Current Alzheimer research
Published: April 30, 2019
Last Updated: 09/26/2026